Biomaterials science : an introduction to materials in medicine / edited by Buddy D. Ratner ... [et al.].

Format:

Book

Contributor:

Ratner, B. D. (Buddy D.), 1947-

Language:

English

Subjects (All):

Biomedical engineering.

Biomedical materials.

Physical Description:

1 online resource (879 p.)

Edition:

2nd ed.

Place of Publication:

Amsterdam ; Boston : Elsevier Academic Press, c2004.

Language Note:

English

Summary:

The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue en

Contents:

Contents; Editors and Lead Contributors; Preface; Introduction: Biomaterials Science: A Multidisciplinary Endeavor; Biomaterials and Biomaterials Science; A History of Biomaterials; Part 1: Materials Science and Engineering; Chapter 1: Properties of Materials; 1.1 Introduction; 1.2 Bulk Properties of Materials; 1.3 Finite Element Analysis; 1.4 Surface Properties and Surface Characterization of Materials; 1.5 Role of Water in Biomaterials; Chapter 2: Classes of Materials Used in Medicine; 2.1 Introduction; 2.2 Polymers; 2.3 Silicone Biomaterials, History and Chemistry

2.4 Medical Fibres and Biotextiles2.5 Hydrogels; 2.6 Applications of 'Smart Polymers' as Biometerials; 2.7 Bioresorable and Bioerodible Materials; 2.8 Natural Materials; 2.9 Metals; 2.10 Ceramics, Glasses and Glass-Ceramics; 2.11 Ptrolytic Carbon for Long-Term Medical Implants; 2.12 Composites; 2.13 Nonfouling Surfaces; 2.14 Physicochemical Surface Modification of Materials Used in Medicine; 2.15 Textured and Porus Materials; 2.16 Surface-Immobilized Biomolecules; Part 2: Biology, Biochemistry, and Medicine; Chapter 3: Some Background Concepts; 3.1 Background concepts

3.2 The Role of Adsorbed Proteins in Tissue Response to Biomaterials3.3 Cells and Cell Injury; 3.4 Tissues, The Extracellular Matrix and Cell-Biomaterial Interactions; 3.5 Mechanical Forces on Cells; Chapter 4: Host Reactions to Biomaterials and Their Evaluation; 4.1 Introduction; 4.2 Inflammation, Wound Healing, and The Foreign-Body Response; 4.3 Innate and Adaptive Immunity: The Immune Response to Foreign Materials; 4.4 The Complement System; 4.5 Systemic Toxicity and Hypersensitivity; 4.6 Blood Coaculation and Blood-Materials Interactions; 4.7 Tumorigenesis and Biomaterials

4.8 Biofilms, Biomaterials and Device-Related InfectionsChapter 5: Biological Testing of Biomaterials; 5.1 Introduction to Testing Biomaterials; 5.2 In Vitro Assessment of Tissue Compatibility; 5.3 In Vivo Assessment of Tissue Compatibility; 5.4 Evaluation of Blood-Materials Interactions; 5.5 Large Animal Models in Cardiac and Vascular Biomaterials Research and Testing; 5.6 Microscopy for Biomaterials Science; Chapter 6: Degradation of Materials in the Biological Environment; 6.1 Introduction: Degradation of Materials in the Biological Environment

6.2 Chemical and Biochemical Degradation of Polymers6.3 Degradative Effects on the Biological Environment on Metals and Ceramics; 6.4 Pathological Calcification of Biomaterials; Chapter 7: Application of Materials in Medicine, Biology, and Artificial Organs; 7.1 Introduction; 7.2 Nonthrombogenic Treatments and Strategies; 7.3 Cardiovascular Medical Devices; 7.4 Implantable Cardiac Assist Devices; 7.5 Artificial Red Blood Cell Substitutes; 7.6 Extracorporeal Artificial Organs; 7.7 Orhopedic Applications; 7.8 Dental Implantation; 7.9 Adhesives and Sealants; 7.10 Ophthalmological Applications

7.11 Intraocular Lens Implants: A Scientific Perspective

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-280-96146-5

9786610961467

0-08-047036-X

OCLC:

243844710