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Host genetic factors that limit HIV and AIDS / Cheryl A. Winkler.
- Format:
- Video
- Author/Creator:
- Winkler, Cheryl A., (SAIC-Frederick, Frederick National Laboratory for Cancer Research, USA), speaker, author.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection.
- The biomedical & life sciences collection, 2056-452X
- Language:
- English
- Subjects (All):
- AIDS (Disease)--Genetic aspects.
- AIDS (Disease).
- HIV infections.
- Acquired Immunodeficiency Syndrome--genetics.
- Acquired Immunodeficiency Syndrome--immunology.
- Genome-Wide Association Study.
- HIV Infections--genetics.
- HIV Infections--immunology.
- Medical Subjects:
- Acquired Immunodeficiency Syndrome--genetics.
- Acquired Immunodeficiency Syndrome--immunology.
- Genome-Wide Association Study.
- HIV Infections--genetics.
- HIV Infections--immunology.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (54 min.)) : color, sound.
- polychrome
- Place of Publication:
- London : Henry Stewart Talks, 2013.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: Overview of candidate gene association studies of HIV and AIDS
- Key role for genetic variants involved in cell entry and host defenses
- Homozygous CCR5 32 basepair deletion prevents HIV Infection
- Acquired Immunity: HLA Class 1 proteins
- Key mediators of HIV progression
- Innate Protection: HLA and KIRS interactions in HIV disease
- Overview of Genome Wide Association Studies (GWAS)
- Overwhelming influence of HLA class I on HIV Progression and control of HIV viral load
- Non-HLA genetic associations with extreme phenotypes
- No new variants identified that prevent HIV infection
- Discovery of chromosome 22 associations with HIV-associated nephropathy
- Future studies
- Epigenetic, proteomic, functional studies
- Potential role of rare variants.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 3301 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
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