Chromosome bi-orientation in yeast / Michael J. R. Stark.

Format:

Video

Author/Creator:

Stark, Michael J. R., speaker, author.

Series:

Henry Stewart talks. Biomedical & life sciences collection. Cell division cycle : controlling when and where cells divide and differentiate.

The cell division cycle : controlling when and where cells divide and differentiate, 2056-452X

Language:

English

Subjects (All):

Cell Cycle.

Genes, cdc.

Medical Subjects:

Cell Cycle.

Genes, cdc.

Genre:

Video recordings.

Physical Description:

1 online resource (1 streaming video file (54 min.)) : color, sound.

polychrome

Place of Publication:

London : Henry Stewart Talks, 2009.

System Details:

Mode of access: World Wide Web.

video file

Contents:

Contents: What is chromosome biorientation and why is it important?

Failure to bi-orient a chromosome will lead to mis-segregation/aneuploidy

Modes of sister chromatid attachment to spindle microtubules

The budding yeast (Saccharomyces cerevisiae) as a model for studying chromosome bi-orientation

Monitoring sister centromeres on individual yeast chromosomes

Kinetochore capture

Achieving chromosome bi-orientation: mechanisms

Geometry-dependent mechanism or a correction mechanism?

Yeast Ipl1p kinase

Chromosomes fail to bi-orient with high frequency in Ipl1 mutants

How might Ipl1p kinase promote bi-orientation?

Yeast chromosomes can bi-orient without the need for back-to-back geometry

How does Ipl1p kinase promote bi-orientation?

The yeast chromosomal passenger complex

Models for tension-sensing

What are the targets of Ipl1p kinase at the kinetochore?

Model for Ipl1 / Aurora function in promoting bi-orientation.

Notes:

Animated audio-visual presentation with synchronized narration.

Title from title frames.

Publisher Number:

2259 Henry Stewart Talks

Access Restriction:

Restricted for use by site license.