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Hox gene regulation in vertebrate hindbrain development / Robb Krumlauf.
- Format:
- Video
- Author/Creator:
- Krumlauf, R. (Robb), Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.
- Epigenetics, chromatin, transcription and cancer, 2056-452X
- Language:
- English
- Subjects (All):
- Developmental genetics.
- Genetic regulation.
- Homeobox genes.
- Neural crest.
- Rhombencephalon.
- Vertebrates--Development.
- Vertebrates.
- Vertebrates--Evolution.
- Body Patterning.
- Gene Expression Regulation, Developmental--physiology.
- Gene Regulatory Networks.
- Genes, Homeobox.
- Neural Crest.
- Rhombencephalon--embryology.
- Rhombencephalon--genetics.
- Vertebrates--embryology.
- Medical Subjects:
- Body Patterning.
- Gene Expression Regulation, Developmental--physiology.
- Gene Regulatory Networks.
- Genes, Homeobox.
- Neural Crest.
- Rhombencephalon--embryology.
- Rhombencephalon--genetics.
- Vertebrates--embryology.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (59 min.)) : color, sound.
- polychrome
- Place of Publication:
- London : Henry Stewart Talks, 2014.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: Origins and diversity of the basic animal body plan
- Ernst Haeckel: Anthropogenie, "Tree of life"
- Common mechanisms for vertebrate body plan
- How does diversity follow from similarity?
- Hox homeotic genes are clustered and control head to tail patterning
- Vertebrate Hox genes display co-linear and segmental expression
- "Hox code"
- Conservation of Hox genes in vertebrates
- The phylotypic stage
- The vertebrate hindbrain, head development and Hox genes: A story in segments
- The nervous system plays an important role in regulating craniofacial development through formation of neural crest cells
- Roles for hindbrain segmentation and neural crest migration in craniofacial patterning
- How are the AP patterns of Hox expression set up?
- Analysis of cis-regulation of HoxB genes
- Modular cis-regulatory control of Hoxa2
- Vertebrate hindbrain segmentation GRN
- Regulation of vertebrate hindbrain organisation
- Previously characterized consensus Hox/Pbx binding sites
- The rhombomere 4 regulatory network
- DV patterns of Hox expression
- Segmental and neuronal functions of Hox genes
- Complex cis-regultory landscape controls Hox gene expression in the specification of axial identity
- Hox genes as integrators of morphogenic information
- Opposing signaling centers drive axial extension: Wnt and Fgf signaling oppose RA signaling
- Regulators of Hox gene expression
- What mechanisms do retinoids use to regulate Hox expression?
- Where are the RAREs and how do they function in the Hox clusters?
- HoxB multiplex reporter BAC reproduces endogenous gene expression pattern
- RAREs are necessary for anterior expansion of 5' Hoxb expression in the neural tube
- Conserved and unique RAREs in Hox clusters
- Is DE-RARE is responsible for the anterior expansion?
- DE-RARE can anteriorize 5' Hoxa gene expression
- Hox genes, retinoids and heart development
- Where are the heart regulatory regions
- Identification of novel HoxB control regions
- Novel RAREs in heart and endoderm enhancers
- Cooperative, shared, selective and long-range enhancers
- Building the gene regulatory network which governs segmental, neuronal and patterning functions of Hox genes.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 3701 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
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