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NK cell signaling to cytotoxicity ; part 1 / Daniel D. Billadeau.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Billadeau, Dan, Speaker.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer.
Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer, 2056-452X
Language:
English
Subjects (All):
Cytotoxicity, Immunologic.
Killer Cells, Natural.
Medical Subjects:
Cytotoxicity, Immunologic.
Killer Cells, Natural.
Genre:
Video recordings.
Physical Description:
1 online resource (1 streaming video file (55 min.)) : color, sound.
polychrome
Other Title:
NK cell signaling to cytotoxicity ; part I
Place of Publication:
London : Henry Stewart Talks, 2010.
System Details:
Mode of access: World Wide Web.
video file
Contents:
Contents: NK cell cytotoxicity
Introduction to NK cell activating receptors
Regulation of NK cell cytotoxicity by immunoreceptor tyrosine-based activation motif associated receptors
The downstream targets regulating NK cytolytic activity
PI3K pathway is required for the development of cellular cytotoxicity
LAT/NTAL are required for DAP12-initiated cytotoxicity and production of interferon gamma
PLCγ2 is required for NK cell killing
Vav proteins are linked to NK cell activating receptors and regulate the development of cellular cytotoxicity
Rho family GTP-binding proteins regulate NK cell-mediated cytotoxicity.
Notes:
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Publisher Number:
2810 Henry Stewart Talks
Access Restriction:
Restricted for use by site license.

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