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Extracellular domain structures from calcium-sensing and GABA(B) receptors / Qing R. Fan.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Fan, Qing R., (Columbia University, USA), speaker, author.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Structural and functional insights into GPCR signalling.
Structural and functional insights into GPCR signalling, 2056-452X
Language:
English
Subjects (All):
Amino acids--Receptors.
Amino acids.
Calcium--Receptors.
Calcium.
Cellular signal transduction.
G proteins--Receptors.
G proteins.
Binding Sites.
GABA-B Receptor Agonists.
GABA-B Receptor Antagonists.
Protein Conformation.
Receptors, Calcium-Sensing--chemistry.
Receptors, Calcium-Sensing--metabolism.
Receptors, GABA-B--chemistry.
Receptors, GABA-B--metabolism.
Receptors, G-Protein-Coupled.
Medical Subjects:
Binding Sites.
GABA-B Receptor Agonists.
GABA-B Receptor Antagonists.
Protein Conformation.
Receptors, Calcium-Sensing--chemistry.
Receptors, Calcium-Sensing--metabolism.
Receptors, GABA-B--chemistry.
Receptors, GABA-B--metabolism.
Receptors, G-Protein-Coupled.
Genre:
Video recordings.
Physical Description:
1 online resource (1 streaming video file (36 min.)) : color, sound.
polychrome
Place of Publication:
London : Henry Stewart Talks, 2019.
System Details:
Mode of access: World Wide Web.
video file
Contents:
Contents: Crystal structures of human GABA(B) receptor extracellular domain in multiple functional states
Agonist vs. antagonist recognition
Identification of novel heterodimer interface associated with receptor activation
Crystal structures of human CaSR in the inactive and active conformations
Discovery of L-amino acids as orthosteric agonists of CaSR
Identification of Ca2+ and PO43 binding sites in CaSR
Universal activation mechanism of class C GPCRs.
Notes:
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Publisher Number:
4777 Henry Stewart Talks
Access Restriction:
Restricted for use by site license.

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