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A paradigm shift in the brain-immune relationships : infiltrating macrophages in central nervous system repair / Michal Schwartz.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Schwartz, Michal (Weizmann Institute of Science, Israel), Speaker.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Macrophage heterogeneity and function.
Macrophage heterogeneity and function : role in innate and adaptive immunity, 2056-452X
Language:
English
Subjects (All):
Brain--Immunology.
Brain.
Central nervous system--Immunology.
Central nervous system.
Macrophages.
Brain--immunology.
Central Nervous System--immunology.
Immune System--physiology.
Immunology.
Medical Subjects:
Brain--immunology.
Central Nervous System--immunology.
Immune System--physiology.
Macrophages.
Genre:
Video recordings.
Physical Description:
1 online resource (1 streaming video file (71 min.)) : color, sound.
polychrome
Place of Publication:
London : Henry Stewart Talks, 2013.
System Details:
Mode of access: World Wide Web.
video file
Contents:
Contents: The CNS immune enigma
CNS response to injury
Recruitment of macrophages is insufficient
Site, dose, timing for macrophage implantation
Local and systemic immune response
Circulating T cells are needed for recovery
Protective autoimmunity vs. autoimmune disease
Two faces of macrophages
Creation of chimeric mice with head protection
Macrophages play anti-inflammatory role
Transferred monocytes promote repair
T-cells boost monocyte recruitment
Macrophages resolve microglia response
The glial scar regulates microglia / macrophages
CSPG production and degradation
CSPG and the IL-10 expressing monocytes
Co-localization of macrophages with the glial scar
Location determines macrophage phenotype
Macrophages and neuroprotection in the retina
Macrophages support progenitor cell renewal
Monocyte recruitment is limited
Type, phenotype, location, timing
Neurogenesis: highest manifestation of plasticity
CNS specific autoreactive T cells
Spatial memory
The immunological malfunction
Immunity to self and self-maintenance
Local and systemic inflammation
Circulating cells fight local inflammation
Recruitment of monocytes in Alzheimer
From immune deficiency to brain malfunction.
Notes:
Animated audio-visual presentation with synchronized narration.
Publisher Number:
3093 Henry Stewart Talks
Access Restriction:
Restricted for use by site license.

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