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The molecular biology of Huntington's disease / David Rubinsztein.
- Format:
- Video
- Author/Creator:
- Rubinsztein, D. C. (David C.), Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Neurodegenerative diseases : fundamentals, research methods, latest advances.
- Neurodegenerative diseases : fundamentals, research methods, latest advances, 2056-452X
- Language:
- English
- Subjects (All):
- Huntington Disease.
- Molecular Biology.
- Neurodegenerative Diseases.
- Medical Subjects:
- Huntington Disease.
- Molecular Biology.
- Neurodegenerative Diseases.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (42 min.)) : color, sound.
- polychrome
- Place of Publication:
- London : Henry Stewart Talks, 2007.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: Clinical presentations of HD
- Pathological features
- Genetic basis
- Trinucleotide repeat expansion mutation
- Huntington protein and cell damage
- Abnormal protein aggregation
- Transcriptional abnormalities
- Raised levels of reactive oxygen species
- Future directions for therapeutic intervention
- siRNA approaches
- Induction of autophagy.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 1052 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
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