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Interleukin-6 : back to the future / Tadamitsu Kishimoto.
- Format:
- Video
- Author/Creator:
- Kishimoto, Tadamitsu (Osaka University, Japan), Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Cytokines.
- Cytokines : intercellular mediators regulating host defense, 2056-452X
- Language:
- English
- Subjects (All):
- Cytokines.
- Interleukin-6.
- Medical Subjects:
- Cytokines.
- Interleukin-6.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (29 min.)) : color, sound.
- polychrome
- Place of Publication:
- London : Henry Stewart Talks, 2011.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: IL-6 is a pleiotropic proinflammatory cytokine
- Its overproduction is involved in inflammatory autoimmune diseases including rheumatoid arthritis
- Blocking of IL-6 signals by anti-IL6 receptor antibody (Tocilizumab) shows therapeutic effect on various autoimmune diseases
- Tocilizumab exerts its effect by inhibiting the induction of a helper T cell subset (TH17)
- Aryl-hydrocarbon receptor (Ahr) is one of the essential molecule for the IL-6 mediated induction of TH17 cells.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 2897 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
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