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The Beta common (betac) family of cytokines, receptors and ligands / Angel Lopez and Timothy Hercus.
- Format:
- Video
- Author/Creator:
- López, Angel (Centre for Cancer Biology, SA Pathology, Australia), Speaker.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Cytokines.
- Cytokines : intercellular mediators regulating host defense, 2056-452X
- Language:
- English
- Subjects (All):
- B cells--Receptors.
- B cells.
- Cytokines--Receptors.
- Cytokines.
- Ligands (Biochemistry).
- Cytokine Receptor Common beta Subunit.
- Ligands.
- Medical Subjects:
- Cytokine Receptor Common beta Subunit.
- Cytokines.
- Ligands.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (40 min.)) : color, sound.
- polychrome
- Other Title:
- The β common (βc) family of cytokines, receptors and ligands title from title slide.
- Place of Publication:
- London : Henry Stewart Talks, 2011.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: Beta common cytokines
- Excessive beta common cytokine function results in inflammatory diseases
- Function through heterodimeric receptors
- The alpha subunits have a conserved architecture
- The beta subunit
- Formation of a soluble GM-CSF receptor complex
- Key interaction between cytokine and beta common, Site 2
- Structure of soluble GM-CSF receptor complex
- Crystal structure revealed a higher-order complex
- Key dodecamer interactions are essential for receptor signalling
- Knowledge of receptor activation mechanism contributes to inhibitor development.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from publisher's website (viewed January 2012).
- Publisher Number:
- 3011 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
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