1 option
DNA methylation / Adrian Bird.
- Format:
- Video
- Author/Creator:
- Bird, A. P., speaker, author.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.
- Epigenetics : concepts, theories, paradigms and mechanisms, 2056-452X
- Language:
- English
- Subjects (All):
- Epigenesis, Genetic.
- Eukaryotic Cells.
- Gene Expression Regulation.
- Transcription, Genetic.
- Medical Subjects:
- Epigenesis, Genetic.
- Eukaryotic Cells.
- Gene Expression Regulation.
- Transcription, Genetic.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (43 min.)) : color, sound.
- polychrome
- Place of Publication:
- London : Henry Stewart Talks, 2007.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: DNA methylation as an epigenetic mark
- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome
- factors determining DNA methylation patterns
- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes
- recruitment of corepressors that impose a silent chromatin structure
- repulsion of transcriptional activators by methyl-CpG leading to gene silencing
- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 1028 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.