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The Eph receptor family / Elena B. Pasquale.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Pasquale, Elena B., speaker, author.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease.
Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, 2056-452X
Language:
English
Subjects (All):
Cellular signal transduction.
Ephrins.
Receptor Protein-Tyrosine Kinases.
Receptors, Eph Family.
Signal Transduction.
Medical Subjects:
Ephrins.
Receptor Protein-Tyrosine Kinases.
Receptors, Eph Family.
Signal Transduction.
Genre:
Video recordings.
Physical Description:
1 online resource (1 streaming video file (36 min.)) : color, sound.
polychrome
Place of Publication:
London : Henry Stewart Talks, 2007.
System Details:
Mode of access: World Wide Web.
video file
Contents:
Contents: Members of the Eph receptor and ephrin ligand families and specificity of binding interactions
Domain structure of Eph receptors and ephrins
Eph receptor-ephrin interactions
Dimerization, tetramerization and further clustering in Eph-ephrin signaling
Tyrosine phosphorylation in Eph-ephrin activation
Modes of signal termination
Eph-ephrin signaling pathways affecting the actin cytoskeleton and cell adhesion: Cell repulsion versus adhesion/attraction, pathways that are activated downstream of Eph receptors
Main Eph effects on cell behavior: shaping and positioning cellular processes and cell migration
Eph receptors in topographic mapping in the visual system
Eph receptors in the organization of axonal projections
Eph receptors in angiogenesis and lymphangiogenesis
Eph receptors in stem cell proliferation and differentiation
Eph receptors in cancer
Eph receptors as drug targets.
Notes:
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Publisher Number:
1112 Henry Stewart Talks
Access Restriction:
Restricted for use by site license.

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