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Imatinib as a paradigm of targeted cancer therapies / Brian J. Druker.
- Format:
- Video
- Author/Creator:
- Druker, Brian J., speaker, author.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease.
- Henry Stewart talks. Biomedical & life sciences collection. Small molecule drug discovery.
- Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, 2056-452X
- Small molecule drug discovery, 2056-452X
- Language:
- English
- Subjects (All):
- Antineoplastic agents.
- Cellular signal transduction.
- Chronic myeloid leukemia--Chemotherapy.
- Chronic myeloid leukemia.
- Protein kinases--Inhibitors.
- Protein kinases.
- Antineoplastic Agents--pharmacology.
- Imatinib Mesylate.
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy.
- Molecular Targeted Therapy.
- Receptor Protein-Tyrosine Kinases.
- Signal Transduction.
- Chemotherapy.
- Medical Subjects:
- Antineoplastic Agents--pharmacology.
- Imatinib Mesylate.
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy.
- Molecular Targeted Therapy.
- Receptor Protein-Tyrosine Kinases.
- Signal Transduction.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (38 min.)) : color, sound.
- polychrome
- Place of Publication:
- London : Henry Stewart Talks, 2007.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: Clinical description of chronic myeloid leukemia (CML)
- Molecular pathogenesis of CML
- The BCR-ABL tyrosine kinase as a therapeutic target
- Preclinical and clinical development of the ABL tyrosine kinase inhibitor, imatinib
- Mechanisms of resistance to imatinib
- Development of novel ABL tyrosine kinase inhibitors for imatinib-resistant CML
- Imatinib and gastrointestinal stromal tumor
- Extending the imatinib paradigm
- Lessons learned from the clinical trials of imatinib.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 1142 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
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