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Elongation of protein synthesis : structural basis of the peptide bond / Marina V. Rodnina.

Henry Stewart Biomedical & Life Sciences Collection Available online

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Format:
Video
Author/Creator:
Rodnina, Marina V., speaker, author.
Series:
Henry Stewart talks. Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.
From DNA to proteins : the multiple levels of regulation, 2056-452X
Language:
English
Subjects (All):
DNA.
Gene Expression Regulation.
Proteins.
Transcription Factors.
Medical Subjects:
DNA.
Gene Expression Regulation.
Proteins.
Transcription Factors.
Genre:
Video recordings.
Physical Description:
1 online resource (1 streaming video file (40 min.)) : color, sound.
polychrome
Place of Publication:
London : Henry Stewart Talks, 2007.
System Details:
Mode of access: World Wide Web.
video file
Contents:
Contents: The ribosome
Chemistry of peptide bond formation
Structure of the peptidyl transferase center of the ribosome
Structures of the catalytic subunit with reaction substrates and transition state analogs
Induced fit in peptide bond formation and peptidyl-tRNA hydrolysis
Reaction pathways of catalyzed and uncatalyzed reactions
pH dependence of catalysis
Entropic catalysis
Role of active site residues
Importance of 2' OH of A76 of the tRNA in the P site
The mechanism of peptide bond formation.
Notes:
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Publisher Number:
1144 Henry Stewart Talks
Access Restriction:
Restricted for use by site license.

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