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β2 adrenergic receptor complexes mediate localized cAMP signaling / Johannes W. Hell.
- Format:
- Video
- Author/Creator:
- Hell, Johannes, 1985- speaker, author.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Ion channels.
- Ion channels : mediators of ion currents across cell membranes, 2056-452X
- Language:
- English
- Subjects (All):
- Beta adrenoceptors.
- Calcium channels.
- Cardiovascular system--Physiology.
- Cardiovascular system.
- Cellular signal transduction.
- Central nervous system--Molecular aspects.
- Central nervous system.
- alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid.
- Calcium Channels, L-Type--physiology.
- Cyclic AMP.
- Neuronal Plasticity.
- Neurons--physiology.
- Receptors, Adrenergic, beta-2--metabolism.
- Receptors, Adrenergic, beta-2--physiology.
- Receptors, AMPA.
- Receptors, Glutamate.
- Signal Transduction--physiology.
- Medical Subjects:
- alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid.
- Calcium Channels, L-Type--physiology.
- Cyclic AMP.
- Neuronal Plasticity.
- Neurons--physiology.
- Receptors, Adrenergic, beta-2--metabolism.
- Receptors, Adrenergic, beta-2--physiology.
- Receptors, AMPA.
- Receptors, Glutamate.
- Signal Transduction--physiology.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (43 min.)) : color, sound.
- polychrome
- Other Title:
- Beta2 adrenergic receptor complexes mediate localized cAMP signaling
- Beta-adrenergic receptor - ion channel signaling complexes
- Place of Publication:
- London : Henry Stewart Talks, 2018.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: Introduction to signaling by beta adrenergic receptors and the corresponding regulation of the L-type calcium channel Cav1.2 in brain and heart
- Cav1.2 signaling complex in brain
- Role of the beta2 adrenergic receptor, Cav1.2, and their association in beta adrenergic signaling in the brain and in synaptic plasticity
- Introduction to the signaling complex formed by the beta2 adrenergic receptor with the AMPA-type glutamate receptor (AMPAR)
- AMPAR signaling complex in brain
- Conclusion: formation of a functional unit between the AMPAR and Cav1.2 whose activity is driven by beta2 adrenergic stimulation to augment synaptic strength in a lasting manner.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Revised version of a talk first published in 2011 under the title: Beta-adrenergic receptor - ion channel signaling complexes.
- Title from title frames.
- Publisher Number:
- 2842 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
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