1 option
Admixture mapping / Paul McKeigue.
- Format:
- Video
- Author/Creator:
- McKeigue, Paul, speaker, author.
- Series:
- Henry Stewart talks. Biomedical & life sciences collection. Genetic epidemiology II : latest developments.
- Genetic epidemiology II : latest developments, 2056-452X
- Language:
- English
- Subjects (All):
- Genetic Predisposition to Disease--epidemiology.
- Medical Subjects:
- Genetic Predisposition to Disease--epidemiology.
- Genre:
- Video recordings.
- Physical Description:
- 1 online resource (1 streaming video file (40 min.)) : color, sound.
- polychrome
- Other Title:
- Title on publisher web site: Admixture mapping : pitfalls and potential
- Place of Publication:
- London : Henry Stewart Talks, 2007.
- System Details:
- Mode of access: World Wide Web.
- video file
- Contents:
- Contents: Applications of statistical modelling of population admixture
- Genetic and environmental explanations for ethnic differences in disease risk
- Methods for finding genes that influence complex traits
- Exploiting admixture to map genes
- Statistical power of admixture mapping
- Advantages of admixture mapping in comparison with other approaches to finding disease susceptibility genes
- Methodological problems of extending linkage analysis of a cross to admixed human populations
- Statistical methods that allow linkage analysis of a cross to be extended to admixed humans
- Model for stochastic variation of ancestry on chromosomes inherited from an admixed parent
- Multipoint inference of ancestry at marker loci from genotypes
- Null hypothesis as graphical model
- Statistical approach to model fitting and hypothesis testing
- The score test algorithm
- Other model diagnostics: "Bayesian p-values"
- How many markers are required for genome-wide admixture mapping?
- Panels of ancestry-informative markers
- Other applications of statistical modelling of admixture.
- Notes:
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Publisher Number:
- 1805 Henry Stewart Talks
- Access Restriction:
- Restricted for use by site license.
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