Precision Cancer Medicine : Challenges and Opportunities / edited by Sameek Roychowdhury, Eliezer M. Van Allen.

Format:

Book

Contributor:

Roychowdhury, Sameek, editor.

Van Allen, Eliezer M., editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Language:

English

Subjects (All):

Cancer--Research.

Cancer.

Cancer Research.

Local Subjects:

Cancer Research.

Physical Description:

1 online resource (VI, 196 pages) : 33 illustrations, 31 illustrations in color

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2019.

System Details:

text file PDF

Summary:

This comprehensive book was written by leading researchers in the emerging and changing field of precision cancer medicine. Precision cancer medicine entails connecting the right molecular diagnosis to the right treatment plan for individual patients. The textbook covers a range of topics from basic science to clinical application for patient care. Precision cancer medicine includes multi-disciplinary fields of research expertise ranging from genomics, pathology, oncology, hereditary genetics, bioinformatics, immunology, cancer biology, and bioethics. Basic topics include molecular diagnostics, liquid biopsy, immunogenomics, drug resistance mechanisms, and bioinformatics analyses of big data. The clinical topics include clinical interpretation, hereditary cancers, designs of basket clinical trials, exceptional responders, and the ethical, legal, and social implications of clinical genomics research. Readers who are involved in one of the specialities of precision cancer medicine can benefit from this book through exposure to other fields. Any level of training or professional practice can benefit from the broad exposure this book can provide. .

Contents:

Preface

Between Hype and Hope, on the Cutting Edge of Precision Cancer Medicine

Molecular Diagnostics in Cancer: a Fundamental Component of Precision Oncology

Clinical Interpretation

Precision Cancer Medicine and Clinical Trial Design

Resistance to Anti-Cancer Therapeutics

Exceptional Responders

Immunogenomics

Managing Germline Findings from Molecular Testing in Precision Oncology

Ethical, legal, and social implications of precision cancer medicine

Liquid Biopsy: Translating Minimally Invasive Disease Profiling From The Lab To The Clinic

Data Portals and Analysis

Index.

Other Format:

Printed edition:

ISBN:

978-3-030-23637-3

9783030236373

Access Restriction:

Restricted for use by site license.