Immunology of the Skin : Basic and Clinical Sciences in Skin Immune Responses / edited by Kenji Kabashima.

Format:

Book

Contributor:

Kabashima, Kenji, editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Language:

English

Subjects (All):

Immunology.

Dermatology.

Infectious diseases.

Infectious Diseases.

Local Subjects:

Immunology.

Dermatology.

Infectious Diseases.

Physical Description:

1 online resource (IX, 510 pages) : 91 illustrations, 7 illustrations in color

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Tokyo : Springer Japan : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

This book reviews the role of each cell subset in the skin, providing the basics for understanding skin immunology and the mechanisms of skin diseases. The skin is one of the immune organs and is continually exposed to foreign antigens and external stimuli that must be monitored and characterized for possible elimination. Upon exposure to foreign antigens, the skin can elicit a variety of immune responses in harmony with skin components that include keratinocytes, dendritic cell subsets, mast cells, basophils, fibroblasts, macrophages, gamma-delta T cells, neutrophils, myeloid-derived suppressor cells, vascular and lymphatic cells, hair follicles, platelets, and adipose tissues, among others. In the past 10 years, knowledge of immunology has expanded drastically in areas such as innate immunity (Toll-like receptors, C-type lectins), and host defenses to bacteria and viruses, and this increased knowledge has led to the development of more effective treatment of psoriasis and other skin diseases. This book provides updates on the mechanisms of skin diseases including contact dermatitis, atopic dermatitis, psoriasis, urticaria, drug eruption, bullous diseases, anaphylaxis, graft-versus-host disease, rosacea, lymphoma, photodermatology, and collagen vascular diseases. Understanding the basics of skin immunology will help clinicians and dermatologists use new therapeutics such as biologics efficiently. Serving as an intermediary between basic science and clinical medicine, this book gives readers the opportunity to understand and marvel at the mystery and fascination of skin immunology.

Contents:

Preface

1 Overview: Immunology of the skin

Part 1 Components of Skin Immune Cells

2 Stratum Corneum

3 Keratinocytes

4 Langerhans cells and dermal dendritic cells

5 T cells

6 gd T cells

7 B cells

8 Mast cells and basophils

9 Neutrophil

10 Macrophages

11 Myeloid derived suppressor cells

12 Lymphatic vessels

13 Hair follicles

14 Platelets

15 Adipose tissues

Part 2 Immune Systems in the Skin

16 Innate immunity

17 C-type lectin receptors

18 Emergence of virulent Staphylococci overriding innate immunity of skin in community

19 Viral infection

20 Contact dermatitis

21 Atopic dermatitis: Common extrinsic and enigmatic intrinsic types

22 Psoriasis

23 Urticaria

24 Cutaneous adverse drug reactions: Stevens-Johnson syndrome and toxic epidermal necrolysis

25 Pemphigus

26 Anaphylaxis

27 Graft Versus Host Disease (GVHD)

28 Rosacea in skin innate immunity

29 Cutaneous Lymphomas

30 Photodermatology- Therapeutic photomedicine for skin diseases

31 Collagen vascular disease

Index.

Other Format:

Printed edition:

ISBN:

978-4-431-55855-2

9784431558552

Access Restriction:

Restricted for use by site license.