My Account Log in

2 options

Prostate Cancer : Cellular and Genetic Mechanisms of Disease Development and Progression / edited by Scott M. Dehm, Donald J. Tindall.

LIBRA Per. v.1 (1967)-v.111 (1979) v.112 (1980)-v.267 (1990), v.269 (1990)-v.330 (1993), v.332 (1993)-v.363 (1995), v.365 (1994)-v.367 (1995), v.369 (1995)-v.370 (1994), v.371B (1995), v.372 (1995)-v.373 (1995), v.375 (1995)-v.401 (1996), v.403 (1996), v.406 (1997), v.408 (1997)-v.482 (2000)-v.483 (2000)
Loading location information...

Available from offsite location This item is stored in our repository but can be checked out.

Log in to request item
Holman Biotech Commons R850.A1 A39 v.484 (2001)-v.506 Pt.A (2002), v.506 Pt.B (2002), v.507 (2002)-v.538 (2003), v.539 Pt.A-B (2003), v.540 (2003)-v.554 (2004), v.557 (2006)-v.561 (2005), v.563 (2005)-v.585 (2006),v.587 (2006)-v.600 (2007), v.601 (2007)-v.611 v.612-v.664,v.669-v.681,v.682-v.687,v.689-v.694,v.696-v.698,v.700-v.730,v.732-v.740,v.742-v.751,v.754-v.758,v.760,v.762-v.765,v.767-v.771,v.774-v.780,v.782-v.788,v.790,v.942,v.946,v.954,v.961,v.970,v.984-v.986,v.990-v.992
Loading location information...

Mixed Availability Some items are available, others may be requested.

Log in to request item
Format:
Book
Contributor:
Dehm, Scott M., editor.
Tindall, Donald J., editor.
SpringerLink (Online service)
Series:
Biomedical and Life Sciences (Springer-11642)
Advances in experimental medicine and biology 0065-2598 ; 1210.
Advances in Experimental Medicine and Biology, 0065-2598 ; 1210
Language:
English
Subjects (All):
Cancer--Research.
Cancer.
Clinical biochemistry.
Cytology.
Proteins.
Systems biology.
Biological systems.
Cancer Research.
Medical Biochemistry.
Cell Biology.
Protein Science.
Receptors.
Systems Biology.
Local Subjects:
Cancer Research.
Medical Biochemistry.
Cell Biology.
Protein Science.
Receptors.
Systems Biology.
Physical Description:
1 online resource (XIII, 476 pages) : 48 illustrations, 44 illustrations in color.
Edition:
Second edition 2019.
Contained In:
Springer eBooks
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2019.
System Details:
text file PDF
Summary:
The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone signaling, and transcriptional regulation, the text covers aspects of prostate cancer from disease initiation to metastasis. Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression, epigenetic regulation of chromatin, and many other topics. This book distinguishes itself from other texts on prostate cancer by its focus on cellular and genetic mechanisms, as opposed to clinical diagnosis and management. As a result, this book will be of broad interest to basic and translational scientists with familiarity of these topics, as well as to trainees at earlier stages of their research careers.
Contents:
Diet and Lifestyle in Prostate Cancer
Dietary Carcinogens and DNA Adducts in Prostate Cancer.-Genetic, Environmental, and Nuclear Factors Governing Genomic
Cells of Origin for Prostate Cancer
Prostate Cancer Genomic Subtypes
Prostate Cancer Transcriptomic Subtypes
Immunological complexity of the prostate cancer microenvironment influences the response to immunotherapy
The Tumor Microenvironments of Lethal Prostate Cancer
The Bone Microenvironment in Prostate Cancer Metastasis
Prostate Cancer Energetics and Biosynthesis
Canonical and Noncanonical Androgen Metabolism and Activity
Germline and Somatic Defects in DNA Repair Pathways in Prostate Cancer
The Role of RB in Prostate Cancer Progression
Interplay among PI3K/AKT, PTEN/FOXO and AR signaling in prostate cancer
Androgen Receptor Dependence
WNT/BETA-CATENIN SIGNALING AND PROSTATE CANCER THERAPY RESISTANCE
Epigenetic Regulation of Chromatin in Prostate Cancer
Oncogenic ETS factors in prostate cancer
Neural Transcription Factors in Disease Progression
Index.
Other Format:
Printed edition:
ISBN:
978-3-030-32656-2
9783030326562
Access Restriction:
Restricted for use by site license.

The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.

Find

Home Release notes

My Account

Shelf Request an item Bookmarks Fines and fees Settings

Guides

Using the Find catalog Using Articles+ Using your account