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RNA Processing : Disease and Genome-wide Probing / edited by Gene W. Yeo.

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Format:
Book
Contributor:
Yeo, Gene W., editor.
SpringerLink (Online service)
Series:
Biomedical and Life Sciences (Springer-11642)
Advances in experimental medicine and biology 0065-2598 ; 907.
Advances in Experimental Medicine and Biology, 0065-2598 ; 907
Language:
English
Subjects (All):
Human genetics.
Human Genetics.
Local Subjects:
Human Genetics.
Physical Description:
1 online resource (XIII, 326 pages) : 37 illustrations, 34 illustrations in color.
Edition:
First edition 2016.
Contained In:
Springer eBooks
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2016.
System Details:
text file PDF
Summary:
Ribonucleic acid (RNA) binding proteins currently number in the thousands and defects in their function are at the heart of diseases such as cancer and neurodegeneration. RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadian rhythm, stem cell self-renewal, oncogenesis and germ cell development. This book surveys a range of genome-wide and systems approaches to studying RNA binding proteins, the importance of RNA binding proteins in development, cancer and circadian rhythm. .
Contents:
Experimental and computational considerations in the study of RNA binding protein-RNA interactions
Genome-wide approaches for RNA structure probing
Tethered function assays as tools to elucidate the molecular roles of RNA binding proteins
Single molecule approaches in RNA-protein interactions
RNA dynamics in the control of circadian rhythm
Roles of RNA binding proteins and post-transcriptional regulation in driving male germ cell development in the mouse
Regulation of stem cell self-renewal and oncogenesis by RNA binding proteins
Controlling the editor: the many roles of RNA binding proteins in regulating A-to-I RNA editing
Mutations in splicing factors and cancer
Regulation of tissue-specific alternative splicing: C. elegans as a model system
RNA Granules and Diseases-A Case Study of Stress Granules in ALS and FTLD
Post-translational modifications and RNA-binding proteins.
Other Format:
Printed edition:
ISBN:
978-3-319-29073-7
9783319290737
Access Restriction:
Restricted for use by site license.

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