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Inflammasome Signaling and Bacterial Infections / edited by Steffen Backert.

Holman Biotech Commons QR1 .E6 v.253 (2001)-v.363,v.367-v.371
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Veterinary: Atwood Library (Campus) QR181 O75 2000
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Format:
Book
Contributor:
Backert, Steffen, editor.
SpringerLink (Online service)
Series:
Biomedical and Life Sciences (Springer-11642)
Current topics in microbiology and immunology 0070-217X ; 397.
Current Topics in Microbiology and Immunology, 0070-217X ; 397
Language:
English
Subjects (All):
Medical microbiology.
Infectious diseases.
Parasitology.
Respiratory organs--Diseases.
Respiratory organs.
Medical Microbiology.
Infectious Diseases.
Pneumology/Respiratory System.
Local Subjects:
Medical Microbiology.
Infectious Diseases.
Parasitology.
Pneumology/Respiratory System.
Physical Description:
1 online resource (XI, 282 pages) : 29 illustrations, 28 illustrations in color.
Edition:
First edition 2016.
Contained In:
Springer eBooks
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2016.
System Details:
text file PDF
Summary:
This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.
Other Format:
Printed edition:
ISBN:
978-3-319-41171-2
9783319411712
Access Restriction:
Restricted for use by site license.

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