C-Type Lectin Receptors in Immunity / edited by Sho Yamasaki.

Format:

Book

Contributor:

Yamasaki, Sho, editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Language:

English

Subjects (All):

Immunology.

Biochemistry.

Pharmaceutical technology.

Biochemistry, general.

Pharmaceutical Sciences/Technology.

Local Subjects:

Immunology.

Biochemistry, general.

Pharmaceutical Sciences/Technology.

Physical Description:

1 online resource (VI, 215 pages) : 29 illustrations, 6 illustrations in color

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Tokyo : Springer Japan : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists.

Contents:

Part 1 ITAM-coupled Activating Receptors

1 Dectin-2 in anti-microbial immunity and homeostasis

2 The function of Mincle as a danger sensor

3 The DAP12-Associated Myeloid C-type Lectin 5A (CLEC5A)

Part 2 HemITAM-bearing Receptors

4 Dectin-1 (CLEC7A, BGR, CLECSF12)

5 DNGR-1, an F-actin-binding C-type lectin receptor involved in cross-presentation of dead cell-associated antigens by dendritic cells

6 C-type lectin-like receptor 2 (CLEC-2)

Part 3 ITIM-bearing Receptors

7 Dendritic cell immunoreceptor (DCIR): An ITIM-harboring C-type lectin receptor

8 Regulation and Function of the Inhibitory C-type Lectin Clec12A/MICL

Part 4 Other receptors and related topics

9 DC-SIGN in infection and immunity

10 LOX-1 and immunity

11 MGL/CD301 as a unique C-type lectin expressed on dendritic cells and macrophages

12 Structural aspects of C-type lectin receptors

13 The Ligands of C-Type Lectins.

Other Format:

Printed edition:

ISBN:

978-4-431-56015-9

9784431560159

Access Restriction:

Restricted for use by site license.