Application of Clinical Bioinformatics / edited by Xiangdong Wang, Christian Baumgartner, Denis C. Shields, Hong-Wen Deng, Jacques S Beckmann.

Format:

Book

Contributor:

Wang, Xiangdong (Professor of clinical bioinformatics), editor.

Baumgartner, Christian (Professor of health care engineering), editor.

Shields, Denis C., editor.

Deng, Hong-wen, editor.

Beckmann, Jacques S., editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Translational bioinformatics 2213-2775 ; 11.

Translational Bioinformatics, 2213-2775 ; 11

Language:

English

Subjects (All):

Medicine.

Bioinformatics.

Medical informatics.

Biomedicine, general.

Health Informatics.

Local Subjects:

Biomedicine, general.

Bioinformatics.

Health Informatics.

Physical Description:

1 online resource (VI, 398 pages) : 120 illustrations, 70 illustrations in color.

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Dordrecht : Springer Netherlands : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.

Contents:

The Era of Big Data: From Data-driven Research to Data-driven Clinical Care

Biostatistics, data mining and computational modeling

Gene expression and profiling

The next generation sequencing and applications in clinical research

Clinical epigenetics and epigenomics

Proteomic profiling: Data mining and analyses

Targeted metabolomics: the next generation of clinical chemistry!?

Clinical bioinformatics for biomarker discovery in targeted metabolomics

Metagenomic Profiling, Interaction of Genomics with Meta-genomics

Clinical Epigenetics and Epigenomics

Integrative Biological Databases

Standards and Regulations for (Bio)Medical Software

Clinical applications and systems biomedicine

Key Law and Policy Considerations for Clinical Bioinformaticians

Challenges and Opportunities in Clinical Bioinformatics

Heterogeneity of Hepatocellular Carcinoma.

Other Format:

Printed edition:

ISBN:

978-94-017-7543-4

9789401775434

Access Restriction:

Restricted for use by site license.