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The Molecular Basis of Autism / edited by S. Hossein Fatemi.

SpringerLink Books Biomedical and Life Sciences 2015 Available online

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Format:
Book
Contributor:
Fatemi, S. Hossein, editor.
SpringerLink (Online service)
Series:
Biomedical and Life Sciences (Springer-11642)
Contemporary clinical neuroscience
Contemporary Clinical Neuroscience
Language:
English
Subjects (All):
Neurosciences.
Psychiatry.
Developmental psychology.
Developmental Psychology.
Local Subjects:
Neurosciences.
Psychiatry.
Developmental Psychology.
Physical Description:
1 online resource (XVIII, 437 pages) : 38 illustrations, 17 illustrations in color.
Edition:
First edition 2015.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Springer, 2015.
System Details:
text file PDF
Summary:
This book is a comprehensive overview of the clinical and scientific aspects of Autism from the leading experts in the field. The clinical section covers everything from epidemiological features to epigenetic regulation to behavioral therapies and much in between. The basic science section presents the latest knowledge on the underlying causes of the disorder including the role of various neurotransmitters, neurexins and neuroligins, reelin, and other proteins. Chapters also explore the cognition and motor control in autism and the connection between oxidative stress and mitochondrial dysfunction and autism. The thorough description of these underlying causes may help researchers and clinicians find more effective treatments and therapies for the 1 in 68 American children who have been diagnosed with Autism.
Contents:
Preface
A Brief History of Autism
Autism Spectrum Disorder: Diagnostic Considerations
Epidemiologic Features of Autism Spectrum Disorders
Genetics of Autism Spectrum Disorders: The Opportunity and Challenge in the Genetics Clinic
Epigenetic Regulation in Autism
Immunology of Autism
Neuroimaging in Autism Spectrum Disorders
The Neuropathology of Autism
Pharmacology of ASD Spectrum Disorder
Behavioral Therapies
Autism and Dopamine
Autism and Glutamate
Serotonin in Autism Spectrum Disorder: Insights From Human Studies and Animal Models
Oxytocin and Vasopressin in Autism and Genetic Syndromes
Molecular basis of cholinergic changes in autistic spectrum disorders and relevance for treatment interventions
Reelin, GABA, FMRP, and Autism
The Role of Neurexins and Neuroligins in Autism
Neurotrophins, their receptors and autism: ligand vs. receptor abnormalities
Cognition, Motor Control and Other Aspects of Autism: A Pragmatic Review
Increased vulnerability to oxidative stress and mitochondrial dysfunction in autism
Index.
Other Format:
Printed edition:
ISBN:
978-1-4939-2190-4
9781493921904
Access Restriction:
Restricted for use by site license.

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