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IgE Antibodies: Generation and Function / edited by Juan J. Lafaille, Maria A. Curotto de Lafaille.
Holman Biotech Commons QR1 .E6 v.253 (2001)-v.363,v.367-v.371
Available
Veterinary: Atwood Library (Campus) QR181 O75 2000
Available
LIBRA v.40 (1967)-v.113 (1984), v.115 (1985)-v.203 (1995), v.205 (1996)-v.252 (2000)
Available from offsite location
Levy Dental Medicine Library - Stacks QR1 .E6 215,271
Mixed Availability
Veterinary: du Pont Library (New Bolton) QR1 .E6 280
Mixed Availability
Veterinary: Atwood Library (Campus) QR1 .E6 271
Mixed Availability
- Format:
- Book
- Series:
- Biomedical and Life Sciences (Springer-11642)
- Current topics in microbiology and immunology 0070-217X ; 388.
- Current Topics in Microbiology and Immunology, 0070-217X ; 388
- Language:
- English
- Subjects (All):
- Immunoglobulins.
- Molecular biology.
- Allergy.
- Parasitology.
- Antibodies.
- Molecular Medicine.
- Allergology.
- Local Subjects:
- Antibodies.
- Molecular Medicine.
- Allergology.
- Parasitology.
- Physical Description:
- 1 online resource (IX, 152 pages) : 21 illustrations, 16 illustrations in color.
- Edition:
- First edition 2015.
- Contained In:
- Springer eBooks
- Place of Publication:
- Cham : Springer International Publishing : Imprint: Springer, 2015.
- System Details:
- text file PDF
- Summary:
- This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.
- Contents:
- Biology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses
- Molecular Mechanisms of IgE Class Switch Recombination
- Anti-IgE Therapy: Clinical Utility and Mechanistic Insights
- New Insights on the Signaling and Function of the High Affinity Receptor for IgE
- Helminth-Induced IgE and Protection Against Allergic Disorders
- IgE Immunotherapy Against Cancer.
- Other Format:
- Printed edition:
- ISBN:
- 978-3-319-13725-4
- 9783319137254
- Access Restriction:
- Restricted for use by site license.
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