Gene Therapy for HIV and Chronic Infections / edited by Ben Berkhout, Hildegund C.J. Ertl, Marc S. Weinberg.

Format:

Book

Contributor:

Berkhout, Ben, editor.

Ertl, Hildegund C. J., editor.

Weinberg, Marc S., editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

American Society of Gene & Cell Therapy, 2626-7713 ; 848.

American Society of Gene & Cell Therapy, 2626-7713 ; 848

Language:

English

Subjects (All):

Gene therapy.

Immunology.

Medicine.

Gene Therapy.

Biomedicine, general.

Local Subjects:

Gene Therapy.

Immunology.

Biomedicine, general.

Physical Description:

1 online resource (XVI, 236 pages) : 41 illustrations, 35 illustrations in color.

Edition:

First edition 2015.

Contained In:

Springer eBooks

Place of Publication:

New York, NY : Springer New York : Imprint: Springer, 2015.

System Details:

text file PDF

Summary:

This volume examines gene therapy and gene transfer approaches to preventing or treating chronic virus infections, focusing on the Big Three viral pathogens- HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV). It explores molecular antiviral strategies, including RNA interference, aptamer-siRNA chimeras, U1i interference, editing CCR5, alternative genetic vaccination by intramuscular gene transfers of virus vectors, and HIV latency in the context of non-coding RNA. This title is a volume of the American Society of Gene and Cell Therapy, a sub-series of the highly successful Advances in Experimental Medicine and Biology. In eleven illustrated chapters, leading international researchers contextualize the structure, operation, and impact of pathogens; examine the existing genetic and molecular research; and extract possible methods of preventing and treating chronic viral infections while evaluating the current body of knowledge. Authoritative and multifaceted, Gene Therapy for HIV and Chronic Infections is an ideal guide for researchers in the fields of gene therapy and immunology interested in expanding their knowledge on how to design an effective gene therapy against a viral pathogen.

Contents:

Gene Therapies for Hepatitis C Virus

Recent Advances in Use of Gene Therapy to Treat Hepatitis B Virus Infection

U1interference (U1i) for antiviral approaches

Gene therapy strategies to block HIV-1 replication by RNA interference

HIV and Ribozymes

Editing CCR5: a novel approach to HIV gene therapy

Synthetic DNA approach to Cytomegalovirus vaccine/immune therapy

Vector-mediated antibody gene transfer for infectious diseases

HIV latency and the non-coding RNA therapeutic landscape

C peptides as entry inhibitors for gene therapy

Aptamer-siRNA chimeras for HIV .

Other Format:

Printed edition:

ISBN:

978-1-4939-2432-5

9781493924325

Access Restriction:

Restricted for use by site license.