The Microtubule Cytoskeleton : Organisation, Function and Role in Disease / edited by Jens Lüders.

Format:

Book

Contributor:

Lüders, Jens, editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Language:

English

Subjects (All):

Cell physiology.

Molecular biology.

Developmental biology.

Cell Physiology.

Molecular Medicine.

Developmental Biology.

Local Subjects:

Cell Physiology.

Molecular Medicine.

Developmental Biology.

Physical Description:

1 online resource (VII, 189 pages) : 20 illustrations, 14 illustrations in color

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Vienna : Springer Vienna : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

This book provides an overview on the organization and function of the microtubule cytoskeleton, which is essential to many cellular processes and profoundly linked to a range of human diseases. Covering basic concepts as well as molecular details, the book discusses how microtubules are nucleated and organized into ordered arrays, at different cell cycle stages and in distinct cell types. In addition, the book highlights how defects in the microtubule cytoskeleton are linked to diseases such as neurodevelopmental disorders. The book is intended for students, graduates and more senior researchers in cell and developmental biology as well as for medical doctors.

Contents:

Part 1. Organization of the microtubule cytoskeleton Microtubule nucleators

Microtubule regulators

Microtubule organizing centers. Part 2. Assembly, maintenance and function of microtubule-based organellesCentrioles/basal bodies

Centrosomes

Cilia. Part 3. The microtubule cytoskeleton and disease Microtubule-based

Centrosome-based

Ciliopathies.

Other Format:

Printed edition:

ISBN:

978-3-7091-1903-7

9783709119037

Access Restriction:

Restricted for use by site license.