Studies on Alzheimer's Disease / edited by Domenico Praticὸ, Patrizia Mecocci.

Format:

Book

Contributor:

Praticò, Domenico, editor.

Mecocci, Patrizia, editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Oxidative stress in applied basic research and clinical practice 2197-7224

Oxidative Stress in Applied Basic Research and Clinical Practice, 2197-7224

Language:

English

Subjects (All):

Oxidative stress.

Cytology.

Geriatrics.

Oxidative Stress.

Cell Biology.

Geriatrics/Gerontology.

Local Subjects:

Oxidative Stress.

Cell Biology.

Geriatrics/Gerontology.

Physical Description:

1 online resource (XI, 236 pages) : 34 illustrations, 29 illustrations in color.

Edition:

First edition 2013.

Contained In:

Springer eBooks

Place of Publication:

Totowa, NJ : Humana Press : Imprint: Humana, 2013.

System Details:

text file PDF

Summary:

Dr. Domenico Praticò received his M.D. from the University of Rome "La Sapienza," School of Medicine. He is currently a Professor of Pharmacology, Microbiology and Immunology and member of the Center for Translational Medicine at Temple University. His main research interest is oxidative biology with a particular focus on bioactive lipids, their metabolic pathways, and their role as biological mediators of cellular and molecular events in the pathogenesis of human diseases, including neurodegenerative and cardiovascular diseases. Dr. Patrizia Mecocci received her M.D. from the University of Perugia, School of Medicine. She is currently a Full Professor of Gerontology and Geriatrics and Director of the Geriatric Clinic at the University of Perugia. Her research is devoted mainly to clinical geriatrics, with a specific interest on brain aging and dementia and on age-related biological modifications, with a particular focus on the role of oxidants and antioxidants in neurodegenerative and cardiovascular diseases. .

Contents:

Section 1: Hypotheses

Oxidative stress: impact in neuroscience research

Oxidative stress and Alzheimer's disease

Inflammation and Oxidation: a link in Alzheimer' disease pathogenesis

GAPDH:β-amyloid mediated iron accumulation in Alzheimer's disease

Aβ in mitochondria: one piece in the Alzheimer's disease puzzle

The role of the plasma membrane redox system in the pathognesis of Alzheimer's disease

Section 2: Mechanisms

Metal dysfunction in Alzheimer's disease

Brain Oxidative Stress in the Pathogenesis and Progression of Alzheimer's Disease

Cholesterol metabolism and oxidative stress in Alzheimer's disease

Brain hypometabolism, oxidative stress, maternal transmission and risk of late-onset Alzheimer's disease

Stress and HPA axis dysfunction in Alzheimer's disease

Section 3: Clinics

Diabetes mellitus and its impact on sporadic Alzheimer's disease

Peripheral biomarkers of oxidative tress in Alzheimer's disease

Nutrition lifestyle and oxidative stress: prevention in Alzheimer's disease

Are antioxidants food and nutrients useful in preventing cognitive decline?.- Antioxidant clinical trials in Mild Cognitive Impairment and Alzheimer's disease.

Other Format:

Printed edition:

ISBN:

978-1-62703-598-9

9781627035989

Access Restriction:

Restricted for use by site license.