Ancestral sequence reconstruction / edited by David A. Liberles.

Format:

Book

Contributor:

Liberles, David A.

Language:

English

Subjects (All):

Nucleotide sequence.

Evolutionary genetics.

Physical Description:

1 online resource (267 p.)

Place of Publication:

New York ; Oxford : Oxford University Press, 2007.

Language Note:

English

Summary:

Ancestral sequence reconstruction is a technique of growing importance in molecular evolutionary biology and comparative genomics. As a powerful tool for testing evolutionary and ecological hypotheses, as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a range of fields. Ancestral Sequence Reconstruction starts with a historical overview of the field, before discussing the potential applications in drug discovery and the pharmaceutical industry. This is followed by a section on computational methodology, which provides a detailed discus

Contents:

Contents; Foreword and introduction; Introduction to the meeting in Kristineberg, Sweden; Contributors; I: Introductory scientific overview; II: Computational methodology and concerns; III: Computational applications of ancestral sequence reconstruction; IV: Experimental methodology and concerns; V: Experimental synthesis of ancestral proteins to test biological hypotheses; Conclusions and a way forward; Index

Notes:

Description based upon print version of record.

Description based on print version record.

Includes bibliographical references and index.

ISBN:

1-4356-2371-1

0-19-153841-8

0-19-171497-6

OCLC:

648359478