NMR-Based Metabolomics : Methods and Protocols / edited by G. A. Nagana Gowda, Daniel Raftery.

Format:

Book

Contributor:

Nagana Gowda, G. A., editor.

Raftery, Daniel, editor.

SpringerLink (Online service)

Series:

Springer Protocols (Springer-12345)

Methods in molecular biology 1064-3745 ; 2037.

Methods in Molecular Biology, 1064-3745 ; 2037

Language:

English

Subjects (All):

Metabolism.

Spectrum analysis.

Metabolomics.

Spectroscopy/Spectrometry.

Local Subjects:

Metabolomics.

Spectroscopy/Spectrometry.

Physical Description:

1 online resource (XIV, 489 pages) : 123 illustrations, 96 illustrations in color.

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

New York, NY : Springer New York : Imprint: Humana, 2019.

System Details:

text file PDF

Summary:

This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understanding, biomarker discovery, environmental studies, and drug discovery to nutrition, while NMR methods include global, targeted, and isotope tracer-based techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, NMR-Based Metabolomics: Methods and Protocols serves as a wealth of information for beginners as well as advanced practitioners and also as stepping stones for further advances in the field of metabolomics.

Contents:

Overview of NMR Spectroscopy-Based Metabolomics: Opportunities and Challenges

Analysis of Plasma, Serum, and Whole Blood Metabolites Using 1H NMR Spectroscopy

Lipid Profiling Using 1H-NMR Spectroscopy

High Resolution Magic Angle Spinning (HRMAS) NMR Methods in Metabolomics

Practical Guidelines for 13C-Based NMR Metabolomics

Analysis of Coenzymes and Antioxidants in Tissue and Blood Using 1D 1H NMR Spectroscopy

UHPLC-QTOF-MS/MS-SPE-NMR: A Solution to the Metabolomics Grand Challenge of Higher-Throughput, Confident Metabolite Identifications

Fast NMR Methods for Identification of Resonances and Metabolic Pathways

Stable Isotope-Resolved Metabolomics by NMR

Tracking Metabolic Rewiring of Cancer Metabolism in Humans Using Isotope-Resolved NMR

NMR-Based Metabolomics in Cardiac Research

Breast Cancer Metabolomics Using NMR

NMR-Based Urinary Metabolomics Applications

NMR-Based Metabolomics in Gallbladder Cancer Research

Biomarker Discovery Using NMR-Based Metabolomics of Tissue

NMR Metabolomics Protocols for Drug Discovery

Practical Aspects of the Analysis of Low- and High-Field NMR Data from Environmental Samples

NMR-Based Metabolomics of Food

Plant Metabolomics Using NMR Spectroscopy

Fast Quantitative 2D NMR for Untargeted and Targeted Metabolomics

Targeted Metabolomics with Quantitative Dissolution Dynamic Nuclear Polarization

Metabolic Profiling Using In Vivo High Field Flow NMR

Tools for Enhanced NMR-Based Metabolomics Analysis

Automated Tools for the Analysis of 1D and 2D NMR Spectra

Processing and Analysis of Untargeted Multi-Cohort NMR Data

Advanced Statistical Methods for NMR-Based Metabolomics.

Other Format:

Printed edition:

ISBN:

978-1-4939-9690-2

9781493996902

Access Restriction:

Restricted for use by site license.