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MicroRNA Target Identification : Methods and Protocols / edited by Alessandro Laganà.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Laganà, Alessandro, editor.
SpringerLink (Online service)
Series:
Springer Protocols (Springer-12345)
Methods in molecular biology 1064-3745 ; 1970.
Methods in Molecular Biology, 1064-3745 ; 1970
Language:
English
Subjects (All):
Human genetics.
Human Genetics.
Local Subjects:
Human Genetics.
Physical Description:
1 online resource (XI, 359 pages) : 119 illustrations, 102 illustrations in color.
Edition:
First edition 2019.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Humana, 2019.
System Details:
text file PDF
Summary:
This detailed book provides a comprehensive state-of-the-art presentation of all aspects of miRNA target identification, from the prediction of miRNA binding sites on their target molecules to their experimental validation and downstream functional analysis. It also explores methodologies and tools for target prediction and related analysis, as well as tutorials on specific tasks, tools, and analysis pipelines. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, MicroRNA Target Identification: Methods and Protocols updates on basic and advanced concepts involving miRNA target identification and delivers an extremely useful guide to specific computational tasks and analysis in miRNA research.
Contents:
A Practical Guide to miRNA Target Prediction
miRandb: A Meta-Database of Online Resources of miRNA and miRNA Targets
Sfold Tools for MicroRNA Target Prediction
The Role of Tertiary Structure in MicroRNA Target Recognition
Protocols for miRNA Target Prediction in Plants
Improving miRNA-Target Prediction Using CLASH Data
Integration of Omics Data to Identify Cancer-Related MicroRNA
Functional Analysis of Genetic Variants and Somatic Mutations Impacting MicroRNA-Target Recognition: Bioinformatics Resources
Construction and Analysis of miRNA Regulatory Networks
Identification of Disease-miRNA Networks across Different Cancer Types Using SWitchMiner (SWIM)
Computational Methods to Investigate the Impact of miRNAs on Pathways
Consensus Target Prediction with Enrichment Analysis for MicroRNAs Harboring Editing Sites and Other Variations
A Roadmap for the Computational Prediction and Experimental Validation of Competitive Endogenous RNAs
Investigating miRNA-lncRNA Interactions: Computational Tools and Resources
Combing the Hairball: Improving Visualization of miRNA-Target Interaction Networks
Inconsistencies and Limitations of Current MicroRNA Target Identification Methods
Experimental Validation of MicroRNA Targets: Luciferase Reporter Assay
Experimental Validation of MicroRNA Targets: Mutagenesis of the Binding Regions
Experimental Validation of MicroRNA Targets: Analysis of MicroRNA Targets through Western Blotting.
Other Format:
Printed edition:
ISBN:
978-1-4939-9207-2
9781493992072
Access Restriction:
Restricted for use by site license.

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