2 options
Snake and Spider Toxins : Methods and Protocols / edited by Avi Priel.
Connect to full text Available online
View onlineHolman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
Available
- Format:
- Book
- Series:
- Springer Protocols (Springer-12345)
- Methods in molecular biology 1064-3745 ; 2068.
- Methods in Molecular Biology, 1064-3745 ; 2068
- Language:
- English
- Subjects (All):
- Pharmacology.
- Pharmacology/Toxicology.
- Local Subjects:
- Pharmacology/Toxicology.
- Physical Description:
- 1 online resource (X, 293 pages) : 46 illustrations, 32 illustrations in color.
- Edition:
- First edition 2020.
- Contained In:
- Springer eBooks
- Place of Publication:
- New York, NY : Springer US : Imprint: Humana, 2020.
- System Details:
- text file PDF
- Summary:
- This volume explores techniques and protocols, across various biological disciplines, used to study snake and spider peptide toxins. The chapters in this book are organized into four parts and cover topics such as the use of toxins in drug development; analysis of bioactivity of complex mixtures like venom; extraction of venom glands and the production of toxins; characterization of toxins from the RNA level to the peptide structure; and the determination of the toxin's biological function. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Snake and Spider Toxins: Methods and Protocols is a valuable resource for both novice and expert researchers who are interested in learning more about this evolving field. .
- Contents:
- Snake- and Spider-Venom-Derived Toxins as Lead Compounds for Drug Development
- Analytics for Bioactivity Profiling of Complex Mixtures with a Focus on Venoms
- Venom Collection from Spiders and Snakes: Voluntary and Involuntary Extractions ("Milking") and Venom Gland Extractions
- Production and Purification of Recombinant Toxins
- RNA-Sequencing of Snake Venom Glands
- Exploring Toxin Evolution: Venom Protein Transcript Sequencing and Transcriptome-Guided High-Throughput Proteomics
- Three-Dimensional Structure Determination of Peptides using Solution Nuclear Magnetic Resonance Spectroscopy
- Determining the Structures of the Snake and Spider Toxins by X-Rays
- MALDI-TOF Mass Spectrometric Profiling of Spider Venoms
- Methods for Evaluation of a Snake Venom Derived Disintegrin in Animal Models of Human Cancer
- Cell-Based Adhesion Assays for Isolation of Snake Venom's Integrin Antagonists
- Using C. elegans to Study the Effects of Toxins in Sensory Ion Channels In Vivo
- Measurements of Cell Death Induced by Snake and Spider's Venoms and Derived Toxins
- Using Toxins in Brain Slice Recordings
- High-Throughput Calcium Imaging Screen of Toxins' Function in Dissociated Sensory Neurons
- Synthesizing and Expressing Native Ion Channels.
- Other Format:
- Printed edition:
- ISBN:
- 978-1-4939-9845-6
- 9781493998456
- Access Restriction:
- Restricted for use by site license.
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.