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Translational Research in Breast Cancer : Biomarker Diagnosis, Targeted Therapies and Approaches to Precision Medicine / edited by Erwei Song, Hai Hu.

LIBRA Per. v.1 (1967)-v.111 (1979) v.112 (1980)-v.267 (1990), v.269 (1990)-v.330 (1993), v.332 (1993)-v.363 (1995), v.365 (1994)-v.367 (1995), v.369 (1995)-v.370 (1994), v.371B (1995), v.372 (1995)-v.373 (1995), v.375 (1995)-v.401 (1996), v.403 (1996), v.406 (1997), v.408 (1997)-v.482 (2000)-v.483 (2000)
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Format:
Book
Contributor:
Song, Erwei, editor.
Hu, Hai, editor.
SpringerLink (Online service)
Series:
Biomedical and Life Sciences (Springer-11642)
Advances in experimental medicine and biology 0065-2598 ; 1026.
Advances in Experimental Medicine and Biology, 0065-2598 ; 1026
Language:
English
Subjects (All):
Cancer--Research.
Cancer.
Cytology.
Cancer Research.
Cell Biology.
Local Subjects:
Cancer Research.
Cell Biology.
Physical Description:
1 online resource (VIII, 418 pages) : 15 illustrations in color.
Edition:
First edition 2017.
Contained In:
Springer eBooks
Place of Publication:
Singapore : Springer Singapore : Imprint: Springer, 2017.
System Details:
text file PDF
Summary:
This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer. With the latest developments in breast cancer research, our understanding of the genomic changes and the oncogenic signaling cascade of breast cancer has made considerable strides. Further, the immuno-environment has been demonstrated as the barrier to clinical cancer. As a result of these two trends, a clearer picture of the molecular landscape of breast cancers has facilitated the development of diagnostic, prognostic and predictive biomarkers for clinical oncology. All these aspects are addressed in this volume, which offers a comprehensive resource for researchers, graduate students and oncologists in cancer research. .
Contents:
Chap. 1 The Dawning of Translational Breast Cancer: from Bench to Bedside
Chap. 2 Biomarker Studies in Early Detection and Prognosis of Breast Cancer
Chap. 3 The Preventive Intervention of Hereditary Breast Cancer
Chap. 4 Predicting and Overcoming Chemotherapeutic Resistance for Breast Cancer
Chap. 5 Studies on DNA Damage Repair and Precision Radiotherapy for Breast Cancer
Chap. 6 Targeted Therapies against Growth Factor Signaling in Breast Cancer
Chap. 7 Targeting Stemness: Implications for Precision Medicine in Breast Cancer
Chap. 8 Disrupting Tumor Angiogenesis and "the Hunger Games" for Breast Cancer
Chap. 9 Key Factors in Breast Cancer Dissemination and Establishment at the Bone: Past, Present and Future Perspectives
Chap. 10 Perspectives of Reprogramming Breast Cancer Metabolism
Chap. 11 Metabolic Changes during Cancer Cachexia Pathogenesis
Chap. 12 Cell Cycle Regulation in Treatment of Breast Cancer
Chap. 13 BRCA Gene Mutations and Poly (ADP-ribose) Polymerase Inhibitors in Triple-negative Breast Cancer
Chap. 14 Targeting the Epigenome as a Novel Therapeutic Approach for Breast Cancer
Chap. 15 Progress in Vaccine Therapies for Breast Cancer
Chap. 16 Tumor Associated Macrophages as Therapeutic Targets for Breast Cancer
Chap 17 New Approaches in CAR-T Cell Immunotherapy for Breast Cancer
Chap 18 Immune Checkpoint Blockade in Breast Cancer Therapy.
Other Format:
Printed edition:
ISBN:
978-981-10-6020-5
9789811060205
Access Restriction:
Restricted for use by site license.

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