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The Drosophila Model in Cancer / edited by Wu-Min Deng.

LIBRA Per. v.1 (1967)-v.111 (1979) v.112 (1980)-v.267 (1990), v.269 (1990)-v.330 (1993), v.332 (1993)-v.363 (1995), v.365 (1994)-v.367 (1995), v.369 (1995)-v.370 (1994), v.371B (1995), v.372 (1995)-v.373 (1995), v.375 (1995)-v.401 (1996), v.403 (1996), v.406 (1997), v.408 (1997)-v.482 (2000)-v.483 (2000)
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Holman Biotech Commons R850.A1 A39 v.484 (2001)-v.506 Pt.A (2002), v.506 Pt.B (2002), v.507 (2002)-v.538 (2003), v.539 Pt.A-B (2003), v.540 (2003)-v.554 (2004), v.557 (2006)-v.561 (2005), v.563 (2005)-v.585 (2006),v.587 (2006)-v.600 (2007), v.601 (2007)-v.611 v.612-v.664,v.669-v.681,v.682-v.687,v.689-v.694,v.696-v.698,v.700-v.730,v.732-v.740,v.742-v.751,v.754-v.758,v.760,v.762-v.765,v.767-v.771,v.774-v.780,v.782-v.788,v.790,v.942,v.946,v.954,v.961,v.970,v.984-v.986,v.990-v.992
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Format:
Book
Contributor:
Deng, Wu-Min, editor.
SpringerLink (Online service)
Series:
Biomedical and Life Sciences (Springer-11642)
Advances in experimental medicine and biology 0065-2598 ; 1167.
Advances in Experimental Medicine and Biology, 0065-2598 ; 1167
Language:
English
Subjects (All):
Cancer--Research.
Cancer.
Molecular biology.
Cytology.
Biomedical engineering.
Cancer Research.
Molecular Medicine.
Cell Biology.
Biomedical Engineering/Biotechnology.
Local Subjects:
Cancer Research.
Molecular Medicine.
Cell Biology.
Biomedical Engineering/Biotechnology.
Physical Description:
1 online resource (VI, 250 pages) : 56 illustrations, 55 illustrations in color.
Edition:
First edition 2019.
Contained In:
Springer eBooks
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2019.
System Details:
text file PDF
Summary:
This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics. Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression. Readers will discover the beauty of the fly model's genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use. This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems. This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.
Contents:
Prelims
Drosophila model in cancer: an introduction
Using Drosophila models and tools to understand the mechanisms of novel human cancer driver gene function
The initial stage of tumorigenesis in Drosophila epithelial tissuesi
Drosophila models of cell polarity and cell competition in tumourigenesis
Two sides of the same coin - compensatory proliferation in regeneration and cancer
P53 and apoptosis in the Drosophila model
Autophagy and tumorigenesis in Drosophila
Filling the gaps among obesity, the CDK8 module, and uterine tumors using Drosophila
MicroRNAs in Drosophila cancer models
Cancer Stem Cells and Stem Cell Tumors in Drosophila
Drosophila as a model for tumor-induced organ wasting
Drosophila melanogaster as a model system for human glioblastomas
What Drosophila Can Teach Us About Radiation Biology of Human Cancers
Drosophila based cancer drug discovery frameworkIn
Index.
Other Format:
Printed edition:
ISBN:
978-3-030-23629-8
9783030236298
Access Restriction:
Restricted for use by site license.

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