7 options
Fc Mediated Activity of Antibodies : Structural and Functional Diversity / edited by Jeffrey V. Ravetch, Falk Nimmerjahn.
Holman Biotech Commons QR1 .E6 v.253 (2001)-v.363,v.367-v.371
Available
Veterinary: Atwood Library (Campus) QR181 O75 2000
Available
LIBRA v.40 (1967)-v.113 (1984), v.115 (1985)-v.203 (1995), v.205 (1996)-v.252 (2000)
Available from offsite location
Levy Dental Medicine Library - Stacks QR1 .E6 215,271
Mixed Availability
Veterinary: du Pont Library (New Bolton) QR1 .E6 280
Mixed Availability
Veterinary: Atwood Library (Campus) QR1 .E6 271
Mixed Availability
- Format:
- Book
- Series:
- Biomedical and Life Sciences (Springer-11642)
- Current topics in microbiology and immunology 0070-217X ; 423.
- Current Topics in Microbiology and Immunology, 0070-217X ; 423
- Language:
- English
- Subjects (All):
- Immunology.
- Cancer--Research.
- Cancer.
- Infectious diseases.
- Cancer Research.
- Infectious Diseases.
- Local Subjects:
- Immunology.
- Cancer Research.
- Infectious Diseases.
- Physical Description:
- 1 online resource (VII, 150 pages) : 14 illustrations, 12 illustrations in color.
- Edition:
- First edition 2019.
- Contained In:
- Springer eBooks
- Place of Publication:
- Cham : Springer International Publishing : Imprint: Springer, 2019.
- System Details:
- text file PDF
- Summary:
- This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
- Contents:
- IgG Fc receptors: evolutionary considerations
- Role of FcgRs in Antibody Based Cancer Therapy
- Anti-inflammatory Activity of IgG-Fc
- IgG Fc glycosylation in human immunity
- IgE Glycosylation in Health and Disease
- Immune Complex Vaccination
- Fc receptors in anti-microbial protection.
- Other Format:
- Printed edition:
- ISBN:
- 978-3-030-31053-0
- 9783030310530
- Access Restriction:
- Restricted for use by site license.
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