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Neuroglia in Neurodegenerative Diseases / edited by Alexei Verkhratsky, Margaret S. Ho, Robert Zorec, Vladimir Parpura.

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Format:
Book
Contributor:
Verkhratskiĭ, A. N. (Alekseĭ Nestorovich), editor.
Ho, Margaret S., editor.
Zorec, Robert, editor.
Parpura, Vladimir, 1964- editor.
SpringerLink (Online service)
Series:
Biomedical and Life Sciences (Springer-11642)
Advances in experimental medicine and biology 0065-2598 ; 1175.
Advances in Experimental Medicine and Biology, 0065-2598 ; 1175
Language:
English
Subjects (All):
Neurosciences.
Neurology.
Molecular biology.
Molecular Medicine.
Local Subjects:
Neurosciences.
Neurology.
Molecular Medicine.
Physical Description:
1 online resource (X, 405 pages) : 58 illustrations, 48 illustrations in color.
Edition:
First edition 2019.
Contained In:
Springer eBooks
Place of Publication:
Singapore : Springer Singapore : Imprint: Springer, 2019.
System Details:
text file PDF
Summary:
This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative process, and as such are essential players in a variety of diseases, including Alzheimer's, Parkinson's, and Huntington's. Intended for researchers and students, the book presents recent advances concerning the biology of neuroglia as well as their interaction with neurons during disease progression. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.
Contents:
Introduction to neuroglia: history, definition, development and main functions
Evolution of astroglia
Physiology of astroglia
Glicoryne system: glial cells as secretory cells of the CNS
Physiology of oligodendroglia and NG-2 glia
Physiology of microglia
General pathophysiology of neuroglia
Neuroglia in ageing
In vivo imaging of neuroglia in neurodegenerative diseases
Astroglia in leukodystrophies
Astrocytes in ALS
Astroglia in Alzheimer's disease
Oligodendrogia in Alzheimer's disease
Microglia in AD
Neuroglia in Parkinson's disease
Neuroglia in Huntington disease
Neuroglia as a therapeutic target
Stem cell derived neuroglia: new tool for research and treatment of neurodegenerative diseases.
Other Format:
Printed edition:
ISBN:
978-981-13-9913-8
9789811399138
Access Restriction:
Restricted for use by site license.

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