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Metabolic Pathway Design : A Practical Guide / by Pablo Carbonell.
- Format:
- Book
- Author/Creator:
- Carbonell, Pablo, 1962- author.
- Series:
- Biomedical and Life Sciences (Springer-11642)
- Learning materials in biosciences 2509-6125
- Learning Materials in Biosciences, 2509-6125
- Language:
- English
- Subjects (All):
- Biomedical engineering.
- Bioinformatics.
- Cytology.
- Systems biology.
- Biological systems.
- Biomedical Engineering/Biotechnology.
- Computational Biology/Bioinformatics.
- Cell Biology.
- Systems Biology.
- Local Subjects:
- Biomedical Engineering/Biotechnology.
- Bioinformatics.
- Computational Biology/Bioinformatics.
- Cell Biology.
- Systems Biology.
- Physical Description:
- 1 online resource (X, 168 pages) : 44 illustrations in color.
- Edition:
- First edition 2019.
- Contained In:
- Springer eBooks
- Place of Publication:
- Cham : Springer International Publishing : Imprint: Springer, 2019.
- System Details:
- text file PDF
- Summary:
- This textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master's students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.
- Contents:
- Part I. Metabolic Pathway Modeling
- Getting on the Path to Engineering Biology
- Genome-Scale Modeling
- Pathway Modeling
- Modeling Chemical Diversity
- Part II. Metabolic Pathway Discovery
- Enzyme Discovery and Selection
- Pathway Discovery
- Pathway Selection
- Part III. Metabolic Pathway Design
- Pathway Design
- Pathway Redesign.
- Other Format:
- Printed edition:
- ISBN:
- 978-3-030-29865-4
- 9783030298654
- Access Restriction:
- Restricted for use by site license.
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