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The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases / edited by Kenneth V. Honn, Darryl C. Zeldin.

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Format:
Book
Contributor:
Honn, Kenneth V., editor.
Zeldin, Darryl C., editor.
SpringerLink (Online service)
Series:
Biomedical and Life Sciences (Springer-11642)
Advances in experimental medicine and biology 0065-2598 ; 1161.
Advances in Experimental Medicine and Biology, 0065-2598 ; 1161
Language:
English
Subjects (All):
Human genetics.
Lipids.
Human physiology.
Cytology.
Cancer--Research.
Cancer.
Molecular biology.
Human Genetics.
Lipidology.
Human Physiology.
Cell Biology.
Cancer Research.
Molecular Medicine.
Local Subjects:
Human Genetics.
Lipidology.
Human Physiology.
Cell Biology.
Cancer Research.
Molecular Medicine.
Physical Description:
1 online resource (IX, 257 pages) : 43 illustrations, 39 illustrations in color.
Edition:
First edition 2019.
Contained In:
Springer eBooks
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2019.
System Details:
text file PDF
Summary:
This book examines the role of bioactive lipids as pro- and anti-inflammatory mediators in the diagnosis of and as novel therapies for cardiovascular disease, cancer, ocular and neurologic diseases, and inflammatory conditions. The major pathways of arachidonic acid and omega-3 fatty acid metabolism are represented, including cyclooxygenases, lipoxygenases, cytochrome P450 monooxygenases, specialized pro-resolving mediators, endocannabinoids, and ceramide and other sphingolipids. This book would be of great interest to basic and translational researchers, as well as physician-scientists working on selected topics (e.g., cancer, cardiovascular disease, stroke, diabetes, inflammation, et cetera) in which the underlying role of lipid mediators in the pathophysiology is known or suspected. This compilation of peer-reviewed manuscripts represents reviews of timely topics presented at the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases. Authors selected are outstanding junior investigators representative of future leaders in the field of bioactive lipids.
Contents:
Prelims
Introduction
Understanding the role of pro-resolving lipid mediators in infectious keratitis
Immunoresolvent resolvin D1 maintains the health of the ocular surface
The evolving role of specialized pro-resolving mediators in modulating neuroinflammation in perioperative neurocognitive disorders
Relationship between specialized pro-resolving mediators and inflammatory markers in chronic cardiac disorders
Specialized pro-resolving mediators directs cardiac healing and repair with activation of inflammation and resolution program in heart failure
Novel n-3 docosapentaneoic acid-derived pro-resolving mediators are vasculoprotective and mediate the actions of statins in controlling inflammation
Aspects of prostaglandin glycerol ester biology
Targeting the COX/mPGES-1/PGE2 pathway in neuroblastoma
Metabolomics biomarkers for precision psychiatry
Cytochrome P450 eicosanoid signaling pathway in colorectal tumorigenesis
Contributions of 12/15-Lipoxygenase to bleeding in the brain following ischemic stroke
Systematic understanding of bioactive lipids in neuro-immune interactions: Lessons from an animal model of multiple sclerosis
Role of bioactive sphingolipids in inflammation and eye diseases
Roles of ceramides and other sphingolipids in immune cell function and inflammation
Acute and chronic mild traumatic brain injury differentially changes levels of bioactive lipids in the CNS associated with headache
Novel anti-inflammatory and vasodilatory ω-3 endocannabinoid epoxide regioisomers
Overview of lipid biomarkers in Amyotrophic Lateral Sclerosis (ALS)
Flavonoids ability to disrupt inflammation mediated by lipid and cholesterol oxidation
Index.
Other Format:
Printed edition:
ISBN:
978-3-030-21735-8
9783030217358
Access Restriction:
Restricted for use by site license.

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