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Prostate cancer : new horizons in research and treatment / edited by Michael L. Cher, Kenneth V. Honn, Avraham Raz.

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Format:
Book
Contributor:
Cher, Michael L.
Honn, Kenneth V.
Raz, Avraham.
Series:
Developments in oncology ; 81.
Developments in oncology ; 81
Language:
English
Subjects (All):
Prostate--Cancer.
Prostate.
Prostate--Tumors.
Physical Description:
1 online resource (VI, 399 p. 149 illus., 30 illus. in color.)
Edition:
1st ed. 2002.
Place of Publication:
Dordrecht ; Boston : Kluwer Academic, c2002.
Summary:
In recent years the pace of research in prostate cancer has increased dramatically. Creative ideas in combination with new and emerging technologies have led to an explosion of discovery. These types of advances in prostate cancer research presage an era of new treatment strategies based on an understanding of the cellular and molecular mechanisms of disease. In creating this book, we aimed to cover a broad "bench to bedside" research spectrum ranging from: genetic, molecular and cellular analyses to epidemiological studies, refinements in local treatment strategies and new biologically based non-hormonal treatments for systemic disease. Researchers and clinicians will find in this book a group of timely and clinically relevant chapters on prostate cancer research and treatment.
Contents:
Pathology of prostate cancer
Prostate cancer susceptibility genes: Many studies, many results, no answers
Molecular profiling in prostate cancer
Chromosomal deletions and tumor suppressor genes in prostate cancer
Role of eicosanoids in prostate cancer progression
Contribution of the androgen receptor to prostate cancer predisposition and progression
Regulation of apoptosis in prostate cancer
On the role of cell surface carbohydrates and their binding proteins (lectins) in tumor metastasis
Metastasis suppression in prostate cancer
The urokinase-type plasminogen activator system in prostate cancer metastasis
Angiogenesis in prostate cancer: Biology and therapeutic opportunities
Integrins and prostate cancer metastases
Prostate carcinoma skeletal metastases: Cross-talk between tumor and bone
Signal transduction targets in androgen-independent prostate cancer
The diet, prostate inflammation, and the development of prostate cancer
Prostate cancer diagnosis, staging and survival
Surgery for prostate cancer: Rationale, technique and outcomes
The future of cancer imaging
Antisense therapy: Current status in prostate cancer and other malignancies
Antiangiogenesis therapeutic strategies in prostate cancer
Chemoprevention of prostate cancer
Prostate brachytherapy
Fast neutron irradiation for prostate cancer
Prostate cancer gene therapy: Past experiences and future promise
Vitamin D-related therapies in prostate cancer
Osteoporosis and other adverse body composition changes during androgen deprivation therapy for prostate cancer.
Notes:
Description based on publisher supplied metadata and other sources.
Includes bibliographical references and index.
ISBN:
0-306-48143-X
OCLC:
614686099

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