Therapeutic Intranasal Delivery for Stroke and Neurological Disorders / edited by Jun Chen, Jian Wang, Ling Wei, John H. Zhang.

Format:

Book

Contributor:

Chen, Jun, editor.

Wang, Jian, Dr., editor.

Wei, Ling, MD, editor.

Zhang, J. H. (John H.), editor.

SpringerLink (Online service)

Series:

Medicine (Springer-11650)

Springer series in translational stroke research 2363-958X

Springer Series in Translational Stroke Research, 2363-958X

Language:

English

Subjects (All):

Neurosciences.

Neurology.

Local Subjects:

Neurosciences.

Neurology.

Physical Description:

1 online resource (VI, 153 pages) : 11 illustrations, 8 illustrations in color.

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2019.

System Details:

text file PDF

Summary:

The blood-brain-barrier prevented harmful materials entering the brain and in the meantime is a barricade to therapeutic drug delivery. Intranasal drug delivery to circumvent blood-brain-barrier was developed in the past, to take advantages of a secret passage from the olfactory epithelium into the brain-bypassing the tight junctions that encapsulated the brain from blood circulation. This timely publication of Therapeutic Intranasal Delivery for Stroke and Neurological Disorders presented some of the latest advances in intranasal delivery research, including transnasal hypothermia induction, stem cell intranasal transplantation, intranasal drug delivery in ischemic and hemorrhagic models, intranasal peptides delivery, intranasal tPA application in adults and children. Editors Jun Chen, Jian Wang, Ling Wei and John Zhang are professors from University of Pittsburgh, Johns Hopkins University, Emory University and Loma Linda University in USA.

Contents:

Preface

Transnasal Induction of Therapeutic Hypothermia for Neuroprotection

Hypoxia-Primed Stem Cell Transplantation in Stroke

Therapeutic potential of intranasal drug delivery in preclinical studies of ischemic stroke and intracerebral hemorrhage

Intranasal Drug Delivery after Intracerebral Hemorrhage

Intranasal Treatment in Subarachnoid Hemorrhage

Intranasal Delivery of Therapeutic Peptides for Treatment of Ischemic Brain Injury

Intranasal delivering method in the treatment of ischemic stroke

Intranasal Delivery of Drugs for Ischemic Stroke Treatment: Targeting IL-17A

Intranasal tPA application for axonal remodeling in rodent stroke and traumatic brain injury models

Therapeutic Intranasal Delivery for Alzheimer's disease

Combination therapy of intranasal IGF-1 and hypothermia

Intranasal Medication Delivery in Children for Brain Disorders

Index.

Other Format:

Printed edition:

ISBN:

978-3-030-16715-8

9783030167158

Access Restriction:

Restricted for use by site license.