Placebos and Nocebos in Headaches / edited by Dimos D. Mitsikostas, Fabrizio Benedetti.

Format:

Book

Contributor:

Mitsikostas, Dimos D., editor.

Benedetti, Fabrizio, editor.

SpringerLink (Online service)

Series:

Medicine (Springer-11650)

Headache,. 2197-652X

Headache, 2197-652X

Language:

English

Subjects (All):

Internal medicine.

Neurology.

Pain medicine.

Internal Medicine.

Pain Medicine.

Local Subjects:

Internal Medicine.

Neurology.

Pain Medicine.

Physical Description:

1 online resource (IX, 142 pages) : 5 illustrations, 3 illustrations in color.

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2019.

System Details:

text file PDF

Summary:

This book discusses the role of placebos and nocebos in the treatment of headache disorders. These disorders are usually treatable, but safety and tolerability issues mean that available preventive treatments have often limited success, even in the right hands - one in five patients treated with a migraine preventive pharmaceutical agent discontinues treatment for those reasons. The nocebo effect plays a role here, with patients' negative expectation and previous unpleasant treatment experiences creating negative belief in the treatment's benefits and safety, which in turn limits treatment outcomes and adherence significantly. In RCTs on migraine prevention, one in 20 patients treated with a placebo discontinued treatment because of adverse events, indicating a considerable nocebo effect; the fewer potential adverse events described in the consent form, the smaller the nocebo effect. As such, physicians treating headache sufferers should acknowledge nocebo as a significant cofactor for treatment adherence and failure, and plan techniques to limit the effects, such as patient education and close follow-up. This highly informative and painstakingly presented book provides scientific insights for professionals and scholars with an interest in internal medicine, neurology and pain medicine. .

Contents:

1 Headache Classification and Diagnosis

2 The burden of headache

3 Patient centred approach in headaches

4 Unmet needs in headache management

5 Mechanisms of pain and headache

6 The reward system

7 Mechanisms of placebo

8 Mechanisms of nocebo

9 Placebo in headache treatment

10 Nocebo in headache treatment. .

Other Format:

Printed edition:

ISBN:

978-3-030-02976-0

9783030029760

Access Restriction:

Restricted for use by site license.