Molecular Diagnostics in Cancer Patients / edited by Kamla Kant Shukla, Praveen Sharma, Sanjeev Misra.

Format:

Book

Contributor:

Shukla, Kamla Kant, editor.

Sharma, Praveen (Of All-India Institute of Medical Sciences), editor.

Misra, Sanjeev, editor.

SpringerLink (Online service)

Series:

Medicine (Springer-11650)

Language:

English

Subjects (All):

Oncology.

Local Subjects:

Oncology.

Physical Description:

1 online resource (VIII, 341 pages) : 45 illustrations, 43 illustrations in color

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Singapore : Springer Singapore : Imprint: Springer, 2019.

System Details:

text file PDF

Summary:

This book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis. The book describes methods and protocols applied in molecular diagnostics. It offers pathologists and researchers providing molecular diagnostic services an array of the most recent and readily accessible reference to compare methods and techniques. Highlights include the molecular diagnosis of genetic aberrations by quantitative polymerase reaction (qPCR), sequence-specific oligonucleotide arrays, next-generation sequencing (NGS), CGH arrays-and methodologies directed at the detection of epigenetic events, high-throughput nucleic acid and protein arrays, direct sequencing and FISH-based methodologies, currently used in the diagnosis of solid tumors. The book also includes an innovative line of treatment in relation to the molecular prognosis, diagnosis and pharmacogenomics in the actual practice of clinical findings at molecular levels. The book covers the applications of numerous genetic testing methodologies; in approximately the chronological order of discovery and high-throughput diagnosis using advanced genomic approaches to identify such genes, in the search for novel drug targets and/or key determinants of drug reactions. It also promotes a wider understanding of molecular diagnostics among physicians, medical students, and scientists in academics, industry and corporate world.

Contents:

Introduction of molecular diagnostics

Molecular Diagnostics in Bladder cancer

Molecular Diagnostics in Lung cancer

Molecular Diagnostics in Brain cancer

Molecular Diagnostics in Melanoma

Molecular Diagnostics in Breast cancer

Molecular Diagnostics in Non-Hodgkin lymphoma

Molecular Diagnostics in Cervical cancer

Molecular Diagnostics in Colorectal cancer

Molecular Diagnostics in Pancreatic cancer

Molecular Diagnostics in Oral cancer

Molecular Diagnostics in Prostate cancer

Molecular Diagnostics in Kidney cancer

Molecular Diagnostics in Skin cancer

Molecular Diagnostics in Leukaemia

Molecular Diagnostics in Thyroid cancer

Molecular Diagnostics in Liver cancer

Molecular Diagnostics in Uterine cancer

Molecular Diagnostics in Ovarian cancer

Pharmacogenomics Testing for Medication and Drug Response.

Other Format:

Printed edition:

ISBN:

978-981-13-5877-7

9789811358777

Access Restriction:

Restricted for use by site license.