Animal Models of Acute Neurological Injury / edited by Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang.

Format:

Book

Contributor:

Chen, Jun, editor.

Xu, Zao C., editor.

Xu, Xiao-Ming, editor.

Zhang, J. H. (John H.), editor.

SpringerLink (Online service)

Series:

Medicine (Springer-11650)

Springer series in translational stroke research 2363-958X

Springer Series in Translational Stroke Research, 2363-958X

Language:

English

Subjects (All):

Neurosciences.

Neurology.

Local Subjects:

Neurosciences.

Neurology.

Physical Description:

1 online resource (X, 544 pages) : 176 illustrations.

Edition:

Second edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2019.

System Details:

text file PDF

Summary:

Despite numerous recent studies and exciting discoveries in the field, only limited treatments are available today for the victims of acute brain and spinal cord injuries. Animal Models of Acute Neurological Injuries, Second Edition, provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that often inhibit advances in this specialized research field. In the 10 years since publication of the first edition of this book, some animal models have become obsolete, some have stood the test of time, and newer models have emerged to enhance our knowledge of acute neurological injuries. The second edition continues to offer the research community tested approaches for this area of investigation. As with the first edition, top experts have developed and contributed these animal models. The book's focus remains hands-on, practical applications of the models, rather than a theoretical approach. Each chapter contains a proven procedure enhanced by clear figures, illustrations, or videos. This new edition presents its readily reproducible protocols with clarity and consistency to best aid neuroscientists and neurobiologists. As with the first edition, the second edition is comprehensive and cutting-edge. Animal Models of Acute Neurological Injuries, Second Edition, is an ideal guide for research professionals, at all stages of their careers, who wish to pursue this vital course of study with the proficiency and precision required by the field.

Contents:

Preface

Animal Protocol

Anesthesia and Analgesia for Research Animals

Rodent Surgical Procedures and Tissue Collection

Brain Monitoring

Veterinary Care Methods for Rats and Mice in Experimental Spinal Cord Injury Studies: An Update

Four Vessel-Occlusion Model in Rats

Rat Model of Global Cerebral Ischemia: Two Vessel-Occlusion (2VO) Model of Forebrain Ischemia

Rodent Model of Pediatric Asphyxial Cardiac Arrest

Transient Middle Cerebral Artery Occlusion Model in Rodents

Targeted Occlusion to Surface and Deep Vessels in Neocortex Via Linear and Nonlinear Optical Absorption

Intraluminal Middle Cerebral Artery Occlusion Model in Mice

Inducing Hemorrhagic Transformation following Middle Cerebral Artery Occlusion via Acute Hyperglycemia in Rats

Cerebral Palsy Model of Uterine Ischemia

Model of Neonatal Focal Cerebral Ischemia-Reperfusion

Monofilament Perforation Subarachnoid Hemorrhage Rat Model

Filament Perforation Subarachnoid Hemorrhage Mouse Model

Non-Human Primate Model of Cerebral Vasospasm

Blood Injection Intracerebral Hemorrhage Rat Model

Collagenase Model of Intracerebral Hemorrhage in Rats

A Rat Model of Cerebellar Hemorrhage using Bacterial Collagenase Injection

Blood Injection Intracerebral Hemorrhage Mouse Model

Blood Injection Intracerebral Hemorrhage Pig Model

Collagenase Induced Pontine Hemorrhage in Rats

Germinal Matrix Hemorrhage Neonatal Rat Model Using Bacterial Collagenase Injection

Fluid Percussion Injury Model

Controlled Cortical Impact Model of Experimental Brain Trauma

Mild Blast-induced Traumatic Brain Injury Model

Rat Model of Surgical Brain Injury

MASCIS Spinal Cord Contusion Model

ESCID Spinal Cord Contusion Model

Cervical Hemicontusion Spinal Cord Injury Model

Applications of the Infinite Horizon Spinal Cord Contusion Injury Model

Clip Impact-Compression Model

Method of Spinal Cord Contusion Injury Created by Tissue Displacement

Experimental Laceration Spinal Cord Injury Model in Rodents

Rodent Spinal Cord Demyelination Models

Spinal Cord Lateral Hemisection and Implantation of Guidance Channels

Spinal Root Avulsion and Repair

Index.

Other Format:

Printed edition:

ISBN:

978-3-030-16082-1

9783030160821

Access Restriction:

Restricted for use by site license.