Diagnosis and Management of Mitochondrial Disorders / edited by Michelangelo Mancuso, Thomas Klopstock.

Format:

Book

Contributor:

Mancuso, Michelangelo, editor.

Klopstock, Thomas, editor.

SpringerLink (Online service)

Series:

Medicine (Springer-11650)

Language:

English

Subjects (All):

Neurology.

Human genetics.

Internal medicine.

Human Genetics.

Internal Medicine.

Local Subjects:

Neurology.

Human Genetics.

Internal Medicine.

Physical Description:

1 online resource (VIII, 382 pages) : 85 illustrations, 52 illustrations in color

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2019.

System Details:

text file PDF

Summary:

This book will help readers navigate the complexity of mitochondrial disorders, by addressing the role of mitochondrial dysfunction and the complex pathophysiological mechanisms associated with a growing number of illnesses, not only of neurological interest. Further, it provides updated concepts on genotype-phenotype correlations, clinical syndromes, diagnostic algorithms and therapies. Written by the world's foremost mitochondrial researchers, the book comprehensively presents the state-of-the-art in mitochondrial medicine, making it of interest to a wide variety of specialists, including neurologists, geneticists, internists and biologists.

Contents:

Mitochondrial Medicine: an Historical Point of View,- Mitochondrial Biology and Function

Mitochondrial Genetics

Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes (MELAS Syndrome)

Myoclonic Epilepsy with Ragged Red Fibers (MERRF Syndrome)

Leber Hereditary Optic Neuropathy (LHON)

Progressive External Ophthalmoplegia (PEO)

Leigh Syndrome

Mitochondrial Depletion Syndromes

Mitochondrial Neurogastrointestinal Encephalopathy (MNGIE)

Mitochondrial Neurodegenerative Disorders I: Dementia and Parkinsonisms

Mitochondrial Neurodegenerative Disorders II: Ataxia and Dystonia, Leukidystrophies

Mitochondria and Heart

Mitochondria and Liver

Mitochondria and Respiratory Involvement

Mitochondrial Endocrinology

Diagnostic Approach to Mitochondrial Disease

Mitochondrial Replacement Approaches

Exercise/Training

Mitochondrial Symptomatic Treatments

Experimental Therapies.

Other Format:

Printed edition:

ISBN:

978-3-030-05517-2

9783030055172

Access Restriction:

Restricted for use by site license.