Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions : Current and Future Trends / edited by Neil H. Shear, Roni P. Dodiuk-Gad.

Format:

Book

Contributor:

Shear, Neil H., editor.

Dodiuk-Gad, Roni P., editor.

SpringerLink (Online service)

Series:

Medicine (Springer-11650)

Language:

English

Subjects (All):

Toxicology.

Drug Safety and Pharmacovigilance.

Pharmacology/Toxicology.

Local Subjects:

Drug Safety and Pharmacovigilance.

Pharmacology/Toxicology.

Physical Description:

1 online resource (XII, 314 pages) : 95 illustrations, 91 illustrations in color

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Singapore : Springer Singapore : Imprint: Adis, 2019.

System Details:

text file PDF

Summary:

This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.

Contents:

Section I. Introduction

1. Introduction: Classification, Terminology, Epidemiology and Etiology of Cutaneous Adverse Drug Reactions

Section II. Pathomechanisms of Cutaneous Adverse Drug Reactions

2. Immunology of Cutaneous Adverse Drug Reactions

3. Pharmacogenomics and Cutaneous Adverse Drug Reactions

4 Viral Reactivation in Cutaneous Adverse Drug Reactions

5. Using Technology to Learn About Immunology of Cutaneous Adverse Drug Reactions

Section III. Clinical Perspectives of Cutaneous Adverse Drug Reactions

6. Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (Epithelial Necrolysis)

7. Drug Reaction with Eosinophilia and Systemic Symptoms

8. Acute Generalized Exanthematous Pustulosis

9. Urticarial Reactions to Drugs

10. Dermatological Adverse Events from Cancer Treatments

11. Cutaneous Adverse Drug Reactions in Pediatric Population

12. Cutaneous Drug Reactions in the Elderly

13. Cutaneous Adverse Drug Reactions in Human Immunodeficiency Virus Patients

14. Cutaneous Adverse Drug Reactions from Anti-Tuberculosis Treatment

Section IV. Approach to the Patient with a Cutaneous Adverse Drug Reaction

15. Practical Approach to Diagnosis and Management of Cutaneous Adverse Drug Reactions

16. Histopathology of Severe Drug Eruptions

17. Evaluation of Drug Safety Literature: A Guide for the Practicing Dermatologist

18. In vitro and in vivo tests in Cutaneous Adverse Drug Reactions

19. Pharmacovigilance of Cutaneous Adverse Drug Reactions

Section V. Epilogue

20. Future Directions and Unmet Research Needs in Cutaneous Adverse Drug Reactions

21. Atlas of Cutaneous Adverse Drug Reactions.

Other Format:

Printed edition:

ISBN:

978-981-13-1489-6

9789811314896

Access Restriction:

Restricted for use by site license.