Dynamic prediction in clinical survival analysis / Hans van Houwelingen, Hein Putter.

Format:

Book

Author/Creator:

Houwelingen, J. C. van, author.

Contributor:

Putter, Hein.

Series:

Monographs on statistics and applied probability ; 123.

Monographs on statistics and applied probability ; 123

Language:

English

Subjects (All):

Proportional hazards models.

Survival analysis (Biometry).

Physical Description:

1 online resource (250 p.)

Edition:

1st ed.

Place of Publication:

Boca Raton, Fla. : CRC Press, 2012.

Boca Raton : CRC Press, 2012.

Language Note:

English

Summary:

In the last twenty years, dynamic prediction models have been extensively used to monitor patient prognosis in survival analysis. Written by one of the pioneers in the area, this book synthesizes these developments in a unified framework. It covers a range of models, including prognostic and dynamic prediction of survival using genomic data and time-dependent information. The text includes numerous examples using real data that is taken from the authors collaborative research. R programs are provided for implementing the methods--Provided by publisher.

Contents:

The special nature of survival data

Cox regression model

Measuring the predictive value of a Cox model

Calibration and revision of Cox models

Mechanisms explaining violation of the Cox model

Non-proportional hazards models

Dealing with non-proportional hazards

Dynamic predictions using biomarkers

Dynamic prediction in multi-state models

Dynamic prediction in chronic disease

Penalized Cox models

Dynamic prediction based on genomic data.

Notes:

"A Chapman & Hall book."

Includes bibliographical references.

Description based on metadata supplied by the publisher and other sources.

ISBN:

0-429-09433-7

1-280-12190-4

9786613525765

1-4398-3543-8

9780429094330

OCLC:

773034860