From molecules to networks : an introduction to cellular and molecular neuroscience / John H. Byrne, Ruth Heidelberger, M. Neal Waxham ; Cristina M. Alberini [and forty four others], contributor.

Format:

Book

Author/Creator:

Byrne, John H., author.

Heidelberger, Ruth, author.

Waxham, M. Neal, author.

Contributor:

Alberini, Cristina M., contributor.

Language:

English

Subjects (All):

Molecular neurobiology.

Cytology.

Neurons.

Nervous system--Cytology.

Nervous system.

Physical Description:

1 online resource (675 p.)

Edition:

Third edition.

Place of Publication:

London : Academic Press, 2014.

Language Note:

English

Summary:

An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. The third edition of "From Molecules to Networks" provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells. In keeping with previous editions, the unique content focus on cellular and molecular neurobiology and related computational neuroscience is maintained and enhanced. All chapters have been thoroughly revised for this third edition to reflect the significant advances of the past five years. The new edition expands on the network aspects of cellular neurobiology by adding new coverage of specific research methods (e.g., patch-clamp electrophysiology, including applications for ion channel function and transmitter release; ligand binding; structural methods such as x-ray crystallography). Written and edited by leading experts in the field, the third edition completely and comprehensively updates all chapters of this unique textbook and insures that all references to primary research represent the latest results. * The first treatment of cellular and molecular neuroscience that includes an introduction to mathematical modeling and simulation approaches * 80% updated and new content * New Chapter on Biophysics of Voltage-Gated Ion Channels * New Chapter on Synaptic Plasticity * Includes a chapter on the Neurobiology of Disease * Highly referenced, comprehensive and quantitative * Full color, professional graphics throughout * All graphics are available in electronic version for teaching purposes

Contents:

Cellular components of nervous tissue / Patrick R. Hof [and others]

Subcellular organization of the nervous system: organelles and their functions / Scott Brady, David R. Colman and Peter Brophy

Energy metabolism in the brain / Gerald A. Dienel

Intracellular signaling / Howard Schulman

Regulation of neuronal gene expression and protein synthesis / Cristina M. Alberini and Eric Klann

Modeling and analysis of intracellular signaling pathways / Paul D. Smolen, Douglas A. Baxter and John H. Byrne

Pharmacology and biochemistry of synaptic transmission: classical transmitters / Ariel Y. Deutch and Robert H. Roth

Nonclassic signaling in the brain / Ariel Y. Deutch, Andrea Giuffrida and James L. Roberts

Connexin and pannexin based channels in the nervous system: gap junctions and more / Juan C. Sâaez and Bruce Nicholson

Neurotransmitter receptors / M. Neal Waxham

Molecular properties of ion channels / Jason Tien [and others]

Membrane potential and action potential / David A. McCormick

Biophysics of voltage-gated ion channels / Diane Lipscombe and Cecilia P. Toro

Dynamical properties of excitable membranes / Douglas A. Baxter and John H. Byrne

Release of neurotransmitter / Robert S. Zucker, Dimitri M. Kullmann and Pascal S. Kaeser

Postsynaptic potentials and synaptic integration / John H. Byrne

Cable properties and information processing in dendrites / Michael Beierlein

Synaptic plasticity / Ruth Heidelberger [and others]

Information processing in neural networks / James J. Knierim

Learning and memory: basic mechanisms / John H. Byrne [and others]

Molecular mechanisms of neurological disease / Monica Gireud, Natalie Sirisaengtaksin and Andrew J. Bean.

Notes:

Previous ed.: 2009.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (ebrary, viewed June 4, 2014).

ISBN:

9780123982674

0123982677

OCLC:

881162131