Toxicology of the skin / edited by Nancy A. Monteiro-Riviere.

Format:

Book

Contributor:

Monteiro-Riviere, Nancy A.

Series:

Target organ toxicology series ; v. 29.

Target organ toxicology series ; 29

Language:

English

Subjects (All):

Dermatotoxicology.

Skin--Diseases.

Skin.

Physical Description:

1 online resource (xiii, 436 pages) : illustrations.

Edition:

First edition.

Place of Publication:

New York : Informa Healthcare, 2010.

Language Note:

English

Summary:

This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barrier may result in damage to the skin or may alter absorption.With contributions from over 40 international experts in the field of skin biology, the book presents the central role of the skin barrier to health and disease.

Contents:

Front Cover; Preface; Contents; Contributors; 1. Structure and Function of Skin; 2. Defensive Functions of the Stratum Corneum: Integrative Aspects; 3. Skin Lipids for Barrier Function; 4. Tight Junctions: A New Barrier in the Skin?; 5. Basic Principles Involved in Quantifying the Dermal Absorption of Topically Applied Chemicals; 6. Chemical Structure-Skin Transport Relationships; 7. Cutaneous Metabolism and Active Transport in Transdermal Drug Delivery; 8. Epidermal Transporters and Metabolism During Dermal Absorption: Importance for Toxicity; 9. Hair Follicle Delivery

10. Structural and Functional Correlations of Skin Barrier in Health and Disease: Models and Evaluation; 11. Are There Differences in Stratum Structure and Function in Different Racial Skin Types?; 12. Skin Absorption Through a Compromised Skin Barrier; 13. The Stratum Corneum in Aged and Photoaged Skin; 14. Cosmetics and Skin Barrier Integrity; 15. Sensing the Environments; 16. Skin Sensitization; 17. Diseases Associated with Cutaneous Barrier Dysfunction: Basic Science Aspects and Clinical Perspectives; 18. Skin Surfactant Proteins: Presence and Potential Defense Functions

19. Liposomes as Promising Tools for the Skin Delivery and Protection of Damaged Skin; 20. Applications of Microneedle Technology to Transdermal Drug Delivery; 21. Emerging Transdermal Drug Delivery Technologies; 22. Nanomaterial Penetration; 23. Potential Arsenic Exposure Through Dermal Penetration; 24. Dermal Absorption and Cutaneous Toxicity of Metalworking Fluids; 25. Cutaneous Bromine Exposure: An Overview and Insight into Postexposure Molecular Responses; 26. Effects of Dermal Exposure to Jet Fuel; 27. Dermal Toxicity of Sulfur Mustard

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on publisher supplied metadata and other sources.

ISBN:

0-429-14687-6

1-282-56101-4

9786612561016

1-4200-7918-2

9780429146879

OCLC:

853364853