Tissue engineering / Clemens A. van Blitterswijk and Jan de Boer, editors ; Ali Khademhosseini [and three others], associate editors ; Laura Zendman, editorial assistant.

Format:

Book

Contributor:

Blitterswijk, Clemens A. van, editor.

Boer, Jan de, 1970- editor.

Khademhosseini, Ali, editor.

Zendman, Laura, editor.

Language:

English

Subjects (All):

Tissue engineering.

Physical Description:

1 online resource (891 p.)

Edition:

Second edition.

Place of Publication:

London, England : Academic Press, 2015.

Language Note:

English

System Details:

text file

Summary:

Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineeri

Contents:

FrontCover; TissueEngineering; Copyright; Contents; Contributors; Preface; Chapter 1 - Tissue Engineering: An Introduction; REFERENCES; Chapter 2 - Stem Cells; LEARNING OBJECTIVES; 2.1 INTRODUCTION; 2.2 DIFFERENTIATION; 2.3 CHARACTERIZATION OF STEM CELLS: SURFACE PROTEIN EXPRESSION; 2.4 CHARACTERIZATION OF STEM CELLS: GENE EXPRESSION; 2.5 METASTABLE STATES OF STEM CELLS; 2.6 PLURIPOTENT STEM CELLS; 2.7 MULTIPOTENT STEM CELLS; 2.8 STEM CELLS IN SKIN EPITHELIA; 2.9 STEM CELLS IN THE INTESTINE; 2.10 STEM CELLS IN THE CENTRAL NERVOUS SYSTEM; 2.11 FUTURE PERSPECTIVES; 2.12 SUMMARY

RECOMMENDED READINGREFERENCES; Chapter 3 - Tissue Formation during Embryogenesis; LEARNING OBJECTIVES; 3.1 INTRODUCTION; 3.2 CARDIAC DEVELOPMENT; 3.3 BLOOD VESSEL DEVELOPMENT; 3.4 DEVELOPMENT OF PERIPHERAL NERVE TISSUE; 3.5 EMBRYONIC SKIN DEVELOPMENT; 3.6 SKELETAL FORMATION; 3.7 FUTURE DIRECTIONS; 3.8 SUMMARY; Chapter 4 - Cellular Signaling; LEARNING OBJECTIVES; 4.1 GENERAL INTRODUCTION; 4.2 CELLULAR SIGNALING IN SKIN BIOLOGY; 4.3 CELLULAR SIGNALING IN VASCULAR BIOLOGY; 4.4 CELLULAR SIGNALING IN BONE BIOLOGY; 4.5 CELLULAR SIGNALING IN SKELETAL MUSCLE; 4.6 FUTURE DEVELOPMENTS

4.7 SNAPSHOT SUMMARYRECOMMENDED READING; REFERENCES; Chapter 5 - Extracellular Matrix as a Bioscaffold for Tissue Engineering; LEARNING OBJECTIVES; 5.1 INTRODUCTION; 5.2 NATIVE EXTRACELLULAR MATRIX; 5.3 ECM SCAFFOLD PREPARATION; 5.4 CONSTRUCTIVE TISSUE REMODELING; 5.5 CLINICAL TRANSLATION OF ECM BIOSCAFFOLDS; COMPOSED OF ECM; 5.7 FUTURE CONSIDERATIONS; 5.8 SUMMARY; Chapter 6 - Degradation of Biomaterials; LEARNING OBJECTIVES; 6.1 DEGRADABLE BIOCERAMICS; 6.2 BIODEGRADABLE POLYMERS; 6.3 FUTURE PERSPECTIVES FOR DEGRADABLE BIOMATERIALS IN TISSUE ENGINEERING; 6.4 SUMMARY; REFERENCES

Chapter 7 - Cell-Material InteractionsLEARNING OBJECTIVES; 7.1 INTRODUCTION; 7.2 SURFACE CHEMISTRY; 7.3 SURFACE TOPOGRAPHY; 7.4 MATERIAL MECHANICS (STIFFNESS); 7.5 SUMMARY; REFERENCES; FURTHER READING; Chapter 8 - Materiomics: A Toolkit for Developing New Biomaterials; LEARNING OBJECTIVES; 8.1 INTRODUCTION: WHAT IS MATERIOMICS?; 8.2 WHY DO WE NEED NEW BIOMATERIALS; 8.3 THE SIZE OF CHEMICAL SPACE; 8.4 DESIGN OF EXPERIMENTS/GENETIC EVOLUTION/PARALLELS TO DRUG DISCOVERY; 8.5 HIGH-THROUGHPUT EXPERIMENTAL METHODS; 8.6 COMPUTATIONAL MODELING; 8.7 FUTURE PERSPECTIVE; 8.8 SUMMARY; REFERENCES

Chapter 9 - Microfabrication Technology in Tissue EngineeringLEARNING OBJECTIVES; 9.1 INTRODUCTION; 9.2 MICROFABRICATION TECHNIQUES IN TISSUE ENGINEERING; 9.3 CONCLUSION AND FUTURE PERSPECTIVE; 9.4 SUMMARY; RECOMMENDED READING; REFERENCES; Chapter 10 - Scaffold Design and Fabrication; LEARNING OBJECTIVES; 10.1 INTRODUCTION; 10.2 SCAFFOLD DESIGN; 10.3 CLASSICAL SCAFFOLD FABRICATION TECHNIQUES; 10.4 ELECTROSPINNING; 10.5 ADDITIVE MANUFACTURING; 10.6 CONCLUSION AND FUTURE DIRECTIONS; RECOMMENDED READING; REFERENCES; Chapter 11 - Controlled Release Strategies in Tissue Engineering

LEARNING OBJECTIVES

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (ebrary, viewed January 10, 2015).

ISBN:

9780124202108

0124202101