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Connexin cell communication channels : roles in the immune system and immunopathology / edited by Ernesto Oviedo-Orta, Brenda R. Kwak, William Howard Evans.
- Format:
- Book
- Language:
- English
- Subjects (All):
- Gap junctions (Cell biology).
- Connexins.
- Inflammation.
- Physical Description:
- 1 online resource (363 p.)
- Edition:
- 1st ed.
- Place of Publication:
- Boca Raton, Fla. : CRC Press, c2013.
- Boca Raton : Taylor & Francis/CRC Press, 2013.
- Language Note:
- English
- Summary:
- Plasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. The book first provides a historical overview of the discovery of these membrane channels in
- Contents:
- Front Cover; Contents; Preface; Editors; Contributors; Prequel: Gap Junctions, Hemichannels, and Cell-to-Cell Signalling; Chapter 1 - Communication in the Immune System by Connexin Channels; Chapter 2 - Gap Junctions and Connexins in the Hematopoietic-Immune System: Structural Considerations; Chapter 3 - Approaches for Studying the Role(s) of Gap Junctions in the Immune System; Chapter 4 - Gap Junctions in Antigen-Presenting Cells; Chapter 5 - Connect the Immune System: Roles of Gap Junctions in Antigen Presentation and T Cell Activation
- Chapter 6 - Gap Junctions and Connexins in the Immune Defense Against TumorsChapter 7 - Connexins in Atherosclerosis; Chapter 8 - Connexins in Lung Function and Inflammation; Chapter 9 - Effect of Oxidative Stress on Connexins in the Vasculature; Chapter 10 - Regulation of Gap Junctions and Cellular Coupling within the Microvasculature in Response to Acute Inflammation; Chapter 11 - Impact of Microglial Activation on Astroglial Connexin Expression and Function in Brain Inflammation; Chapter 12 - A Role for Connexins in Inflammatory Disorders of the Epidermis
- Chapter 13 - Translating Basic Research on Cx43 Gap Junctions into Therapies for Reducing Scarring and Cardiac ArrhythmiaChapter 14 - Connexin-Based Therapeutic Approaches to Inflammation in the Central Nervous System; Chapter 15 - Enhancing Epithelial Tissue Repair and Reducing Inflammation by Targeting Connexins; Back Cover
- Notes:
- Description based upon print version of record.
- Includes bibliographical references.
- Description based on online resource; title from title page (ebrary, viewed April 12, 2013).
- ISBN:
- 9781040212318
- 104021231X
- 9780429165856
- 0429165854
- 9781439862582
- 1439862583
- OCLC:
- 831118576
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